OBM Neurobiology is an international peer-reviewed Open Access journal published quarterly online by LIDSEN Publishing Inc. By design, the scope of OBM Neurobiology is broad, so as to reflect the multidisciplinary nature of the field of Neurobiology that interfaces biology with the fundamental and clinical neurosciences. As such, OBM Neurobiology embraces rigorous multidisciplinary investigations into the form and function of neurons and glia that make up the nervous system, either individually or in ensemble, in health or disease. OBM Neurobiology welcomes original contributions that employ a combination of molecular, cellular, systems and behavioral approaches to report novel neuroanatomical, neuropharmacological, neurophysiological and neurobehavioral findings related to the following aspects of the nervous system: Signal Transduction and Neurotransmission; Neural Circuits and Systems Neurobiology; Nervous System Development and Aging; Neurobiology of Nervous System Diseases (e.g., Developmental Brain Disorders; Neurodegenerative Disorders).

OBM Neurobiology publishes research articles, technical reports and invited topical reviews. Although the OBM Neurobiology Editorial Board encourages authors to be succinct, there is no restriction on the length of the papers. Authors should present their results in as much detail as possible, as reviewers are encouraged to emphasize scientific rigor and reproducibility.

Archiving: full-text archived in CLOCKSS.

Rapid publication: manuscripts are undertaken in 11.8 days from acceptance to publication (median values for papers published in this journal in the second half of 2021, 1-2 days of FREE language polishing time is also included in this period).

Current Issue: 2023  Archive: 2022 2021 2020 2019 2018 2017

Special Issue

Recent Advances in Psychiatry

Submission Deadline: December 30, 2020 (Open) Submit Now

Guest Editor

Laura Orsolini

1. Department of Neurosciences/DIMSC, Unit of Psychiatry, School of Medicine, Polytechnic University of Marche, Ancona, Italy;
2. Psychopharmacology, Drug Misuse and Novel Psychoactive Substances Research Unit, School of Life and Medical Sciences, University of Hertfordshire, College Lane Campus, Hatfield, Herts AL10 9AB, UK.

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Research Interests: Clinical Psychiatry; Psychopathology; Psychopharmacology; Addiction Medicine; Psychiatric Rehabilitation; Neurosciences

About This Topic

The increasing interest and advances in both diagnostic and therapeutic technological devices (e.g., structural and functional MRI, ECT, tDCS, rTMS, etc.), the studies in the field of the Default Mode Network (DMN), the identification and application of specific biomarkers for mental illness in the clinical practice, the investigation of the field of the neuroinflammation and its role in the mental disorders, the neuroimaging studies and the development of a plethora of new therapeutic psychopharmacological targets, has allowed the implementation of new research trajectories.

In this special issue, we welcome any papers specifically focusing on the recent advances in psychiatry, e.g., neuroimaging studies in mental disorders; translational psychiatry; personalized psychiatry; studies on the therapeutic neuromodulation in psychiatry such as transcranial direct current stimulation (tDCS), ripetitive transcranial magnetic stimulation (rTMS), deep brain stimulation (DBS), vagal nerve stimulation (VNS) and the electroconvulsive therapy (ECT), studies on DMN, on the recent advances in psychopharmacology. Original research reports, review articles, communications, and perspectives are welcome in all areas pertinent to this topic. All accepted papers will be published free of charge.


Manuscripts should be submitted online at http://www.lidsen.com/account-login by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website. Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. Guidelines for authors and other relevant information for submission of manuscripts are available on the Instructions for Authors page. OBM Neurobiology is an international peer-reviewed Open Access monthly journal published by LIDSEN. Please visit the Instructions for Authors page before submitting a manuscript.


Neuroscience; Psychiatry; Psychopharmacology; New Psychiatric Therapies; Personalized Psychiatry; Neuroimaging; Neuroinflammation

Planned Papers

Title: Psychiatric disorders associated with dysfunctional mTOR pathway signaling: an update
Affiliation: University Hospital Centre, Poitiers, France

Title: Psychiatric disorders in Mӧbius sequence: intermittent presentation of auto-aggressive outbursts
Authors: Vincenzo Prisco 1,  Bernadette Donnarumma 2, Lorenzo Prisco 3
1. Department of Psychiatry ASL Naples 1, Professor at University Federico II, Naples, Italy
2. Resident in Pediatrics, University Federico II, Naples, Italy
3. Emergency medical Service ASL Salerno, Italy

Title: The Role of Humor in Psychotherapy: Funny Pathways
Authors: Frank Rodden, Wilibald Ruch, Jenny Hofman
Affiliation: University of Zurich, Zurich, Switzerland


Open Access Case Report

Psychiatric Disorders in Mӧbius Sequence: Intermittent Presentation of Auto-Aggressive Outbursts

Received: 27 March 2020;  Published: 03 December 2020;  doi: 10.21926/obm.neurobiol.2004079


Anecdotal evidence suggests the possible association of psychiatric disorders with Mӧbius sequence, although the evidence is not conclusive. Intermittent presentation of auto-aggressive outbursts, in particular, could be related to Mӧbius sequence, different from the common psychotic symptoms. The present report describes the clinical case [...]
Open Access Original Research

Variations in Secondary Health Resource Utilization Post Clozapine Initiation

Received: 10 September 2020;  Published: 26 November 2020;  doi: 10.21926/obm.neurobiol.2004078


This study looked at secondary care utilization metrics as an effectiveness indicator of Clozapine initiation in 77 patients over the following year compared to the year prior to initiation. It was found that there was a marginal drop in psychiatric bed utilization, alongside reduced crisis team use. Medical and psychiatric outpatient use [...]