OBM Neurobiology is an international peer-reviewed Open Access journal published quarterly online by LIDSEN Publishing Inc. By design, the scope of OBM Neurobiology is broad, so as to reflect the multidisciplinary nature of the field of Neurobiology that interfaces biology with the fundamental and clinical neurosciences. As such, OBM Neurobiology embraces rigorous multidisciplinary investigations into the form and function of neurons and glia that make up the nervous system, either individually or in ensemble, in health or disease. OBM Neurobiology welcomes original contributions that employ a combination of molecular, cellular, systems and behavioral approaches to report novel neuroanatomical, neuropharmacological, neurophysiological and neurobehavioral findings related to the following aspects of the nervous system: Signal Transduction and Neurotransmission; Neural Circuits and Systems Neurobiology; Nervous System Development and Aging; Neurobiology of Nervous System Diseases (e.g., Developmental Brain Disorders; Neurodegenerative Disorders).

OBM Neurobiology publishes a variety of article types (Original Research, Review, Communication, Opinion, Comment, Conference Report, Technical Note, Book Review, etc.). Although the OBM Neurobiology Editorial Board encourages authors to be succinct, there is no restriction on the length of the papers. Authors should present their results in as much detail as possible, as reviewers are encouraged to emphasize scientific rigor and reproducibility.

Publication Speed (median values for papers published in 2023): Submission to First Decision: 7.5 weeks; Submission to Acceptance: 15.9 weeks; Acceptance to Publication: 7 days (1-2 days of FREE language polishing included)

Current Issue: 2024  Archive: 2023 2022 2021 2020 2019 2018 2017

Special Issue

Autoradiography: Past and Emerging Technologies to Map Receptors/Enzymes and Their Functions

Submission Deadline: December 31, 2022 (Open) Submit Now

Guest Editor

Najam Sharif, PhD, DSc

Global Alliance and External Research, Santen Inc., Emeryville, CA 94608, USA.

Adjunct Professor, University of North Texas (USA), Duke-NUS Medical School (Singapore).

Website | E-Mail

Research interests: neurological diseases; therapeutics; retina and brain connections; glaucomatous optic neuropathy; optic nerve; pharmacology; drug discovery.

About This Topic

Use of radioligands to display and evaluate their binding sites within body cells and tissues has a rich history from simply mapping the presence of receptors/enzymes/transporters to use as diagnostic agents. Since significant technological advances have occurred over the last 3-4 decades, it is important to capture and disseminate the wealth of knowledge that has accumulated. Techniques and tools ranging from digital subtraction quantitative methods, pharmacological evaluation of compounds in un-dissectible cells/tissues, phosphor imaging, generation and utility of novel radioisotopes for imaging, imaging of receptor function in response to drugs and transmitters in vitro, and functional imaging in living animals and humans using positron emission tomography have evolved that can shed light on normal vs diseased conditions and reveal drug delivery challenges and solutions and provide insights to side-effect potential of drugs. Receptor/enzyme localization is critical for verifying target engagement in cells and tissues impacting different body organs but in particular the brain, spinal cord, optic nerve and retina, areas of focus of this Special Issue. Authors working in these fields of study are encouraged to submit their original research papers or review articles with emphasis on tissues and organs mentioned above.

Manuscript Submission Information

Manuscripts should be submitted through the LIDSEN Submission System. Detailed information on manuscript preparation and submission is available in the Instructions for Authors. All submitted articles will be thoroughly refereed through a single-blind peer-review process and will be processed following the Editorial Process and Quality Control policy. Upon acceptance, the article will be immediately published in a regular issue of the journal and will be listed together on the special issue website, with a label that the article belongs to the Special Issue. LIDSEN distributes articles under the Creative Commons Attribution (CC BY 4.0) License in an open-access model. The authors own the copyright to the article, and the article can be free to access, distribute, and reuse provided that the original work is correctly cited.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). Research articles and review articles are highly invited. Authors are encouraged to send the tentative title and abstract of the planned paper to the Editorial Office (neurobiology@lidsen.com) for record. If you have any questions, please do not hesitate to contact the Editorial Office.

Welcome your submission!