OBM Neurobiology is an international peer-reviewed Open Access journal published quarterly online by LIDSEN Publishing Inc. By design, the scope of OBM Neurobiology is broad, so as to reflect the multidisciplinary nature of the field of Neurobiology that interfaces biology with the fundamental and clinical neurosciences. As such, OBM Neurobiology embraces rigorous multidisciplinary investigations into the form and function of neurons and glia that make up the nervous system, either individually or in ensemble, in health or disease. OBM Neurobiology welcomes original contributions that employ a combination of molecular, cellular, systems and behavioral approaches to report novel neuroanatomical, neuropharmacological, neurophysiological and neurobehavioral findings related to the following aspects of the nervous system: Signal Transduction and Neurotransmission; Neural Circuits and Systems Neurobiology; Nervous System Development and Aging; Neurobiology of Nervous System Diseases (e.g., Developmental Brain Disorders; Neurodegenerative Disorders).
OBM Neurobiology publishes research articles, technical reports and invited topical reviews. Although the OBM Neurobiology Editorial Board encourages authors to be succinct, there is no restriction on the length of the papers. Authors should present their results in as much detail as possible, as reviewers are encouraged to emphasize scientific rigor and reproducibility.
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Rapid publication: manuscripts are undertaken in 11.8 days from acceptance to publication (median values for papers published in this journal in the second half of 2021, 1-2 days of FREE language polishing time is also included in this period).
The Pathophysiology and Treatment for Migraine
Submission Deadline: May 31, 2022 (Open) Submit Now
Yasushi Shibata, MD, PhD
Professor, Department of Neurosurgery
Mito Medical Center, University of Tsukuba
Mito Kyodo General Hospital, Japan
Research Interests: Brain injury; brain tumor; cerebrovascular disease; radiological diagnosis; headache; MRI; SPECT; migraine; critical pathway
About This Topic
The pathophysiology of migraines is not completely understood, although migraines are a common disease. Because a clinically useful biomarker or laboratory test for the diagnosis of migraines has not been established, a clinical diagnosis of migraine is currently made based only on the symptoms. The recent advances in neuroimaging and laboratory tests have improved the understanding of the pathophysiology of migraines. These researches may provide useful biomarkers for the diagnosis and monitoring of migraines.
Recently the treatment of migraines has dramatically changed by the appearance of novel medicine and neuromodulation devices. This special issue collected cutting edge research articles on migraine. All readers and the clinical practitioners will understand the current progress of migraine research, and could help the patient with migraine to cope with their headache.
Received: 18 May 2022; Published: 16 August 2022; doi: 10.21926/obm.neurobiol.2203131
This citizen science project CLUE compared the attack frequency between school and vacation periods among adolescents. The data collection process adopted in citizen science projects opens up the possibility of conducting analyses by including a large number of participants over a long period and across different regions.
Received: 25 October 2021; Published: 08 February 2022; doi: 10.21926/obm.neurobiol.2201115
Magnetic resonance imaging (MRI) has been used to investigate migraine pathophysiology because it is a non-invasive technique. The main aim of clinical imaging for patients with headaches is to exclude secondary headaches due to organic lesions. Conventional structural imaging techniques such as routine MRI demonstrate white matter lesions [...]
Received: 24 June 2021; Published: 20 December 2021; doi: 10.21926/obm.neurobiol.2104111
Circadian rhythms are 24-hour cycles of physical, mental, and behavioral changes regulated and maintained by the internal primary circadian clock, however modifiable by a number of external cues or “zeitgebers”, the most powerful one being light. Core set of clock genes regulate the whole-body metabolism and transcription of [...]
by Niamh Flynn
Received: 18 March 2021; Published: 02 May 2021; doi: 10.21926/obm.neurobiol.2102092
Although studies to understand the pathogenesis of migraines are in progress, no theory has adequately explained the etiology and pathophysiology of migraines to date. This has affected the development of treatment strategies for migraineurs. Currently, the pharmacological treatment for migraines provides both acute and prophylacti [...]
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