by Oleksandr M. Stoyanov  , Valeriy Y. Kalashnikov  , Rooslan S. Vastyanov  , Yevgen V. Oprya  , Yuriy V. Melnyk  , Yana I. Kuhel  and Tamara O. Andreeva

Received: 09 March 2026;  Published: 06 July 2026;  doi: 10.21926/obm.neurobiol.2603340

The article presents a comprehensive clinical, neurological, and neuropsychological analysis of chronic alcoholic encephalopathy (CAE) as a systemic toxic-metabolic lesion of the central nervous system, characterized by a stage-dependent progressive course that is not a direct equivalent of the stages of alcohol dependence. Based on the examination of 66 patients with CAE of varying severity, the disease is shown to involve a combination of diffuse neurological symptoms (cerebellar, vestibular, [...]