OBM Geriatrics is an Open Access journal published quarterly online by LIDSEN Publishing Inc. The journal takes the premise that innovative approaches – including gene therapy, cell therapy, and epigenetic modulation – will result in clinical interventions that alter the fundamental pathology and the clinical course of age-related human diseases. We will give strong preference to papers that emphasize an alteration (or a potential alteration) in the fundamental disease course of Alzheimer’s disease, vascular aging diseases, osteoarthritis, osteoporosis, skin aging, immune senescence, and other age-related diseases.
Geriatric medicine is now entering a unique point in history, where the focus will no longer be on palliative, ameliorative, or social aspects of care for age-related disease, but will be capable of stopping, preventing, and reversing major disease constellations that have heretofore been entirely resistant to interventions based on “small molecular” pharmacological approaches. With the changing emphasis from genetic to epigenetic understandings of pathology (including telomere biology), with the use of gene delivery systems (including viral delivery systems), and with the use of cell-based therapies (including stem cell therapies), a fatalistic view of age-related disease is no longer a reasonable clinical default nor an appropriate clinical research paradigm.
Precedence will be given to papers describing fundamental interventions, including interventions that affect cell senescence, patterns of gene expression, telomere biology, stem cell biology, and other innovative, 21st century interventions, especially if the focus is on clinical applications, ongoing clinical trials, or animal trials preparatory to phase 1 human clinical trials.
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Stroke in Older Adults
Submission Deadline: January 15, 2021 (Open) Submit Now
David G Smithard, BSc, MB, MD, FRCP, FRCSLT(Hon)
Consultant in Elderly and Stroke Medicine, Geriatric Medicine, Queen Elizabeth Hospital, Lewisham and Greenwich NHS Trust, Woolwich, SE18 4QH, UK;
Research Fellow, Department of Sports Science, University of Greenwich, London, SE9 2UG, UK
Research Interests: Dysphagia; frailty; care homes; stroke; swallowing rehabilitation; healthy aging
About This Topic
Although stroke is a medical problem affecting all age groups, older adults are particularly affected. Many studies fail to include very old adults and it is questionable as to whether the pharmacological management of acute stroke or interventional treatments are appropriate in the frail older people.
All papers are welcome but particularly papers in the following areas:
Access and approach to care may vary depending on race, ethnicity or where you live. Papers exploring these issues are particularly welcome.
The appropriateness and applicability of secondary prevention medication use in frail older adults.
The management of stroke in Nursing Home residents.
The attitudes of health care staff towards frail older adults affected by acute stroke.
The psychological effects of stroke in older frail adults.
Risk factor management in frail older people.
Preadmission frailty and under-nutrition and stroke.
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