(ISSN 2638-1311)
OBM Geriatrics is an international peer-reviewed Open Access journal published quarterly online by LIDSEN Publishing Inc. The journal takes the premise that innovative approaches – including gene therapy, cell therapy, and epigenetic modulation – will result in clinical interventions that alter the fundamental pathology and the clinical course of age-related human diseases. We will give strong preference to papers that emphasize an alteration (or a potential alteration) in the fundamental disease course of Alzheimer’s disease, vascular aging diseases, osteoarthritis, osteoporosis, skin aging, immune senescence, and other age-related diseases.
Geriatric medicine is now entering a unique point in history, where the focus will no longer be on palliative, ameliorative, or social aspects of care for age-related disease, but will be capable of stopping, preventing, and reversing major disease constellations that have heretofore been entirely resistant to interventions based on “small molecular” pharmacological approaches. With the changing emphasis from genetic to epigenetic understandings of pathology (including telomere biology), with the use of gene delivery systems (including viral delivery systems), and with the use of cell-based therapies (including stem cell therapies), a fatalistic view of age-related disease is no longer a reasonable clinical default nor an appropriate clinical research paradigm.
Precedence will be given to papers describing fundamental interventions, including interventions that affect cell senescence, patterns of gene expression, telomere biology, stem cell biology, and other innovative, 21st century interventions, especially if the focus is on clinical applications, ongoing clinical trials, or animal trials preparatory to phase 1 human clinical trials.
Papers must be clear and concise, but detailed data is strongly encouraged. The journal publishes a variety of article types (Original Research, Review, Communication, Opinion, Comment, Conference Report, Technical Note, Book Review, etc.). There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.
Publication Speed (median values for papers published in 2024): Submission to First Decision: 6.3 weeks; Submission to Acceptance: 11.4 weeks; Acceptance to Publication: 7 days (1-2 days of FREE language polishing included)
Special Issue
Incontinence Among Older Adults
Submission Deadline: November 30, 2022 (Closed)
Guest Editor
Ron J. Jankowski, PhD
Vice President, Scientific Affairs, Cook MyoSite Inc, 105 Delta Dr, Pittsburgh, PA 15238 USA
Research Interests: Autologous muscle derived cells; incontinence; cell therapies; translational medical and biologic product development
Co-Editor
Michael B. Chancellor, MD
Professor and Director of Neurourology, Department of Urology, Beaumont Health System, Oakland University William Beaumont School of Medicine, Royal Oak, MI 84073, USA
Research Interests: Incontinence; neurourology; female urology; urology; stem cell and tissue engineering; drug discovery; lower urinary tract dysfunction; adult autologous muscle-derived stem cells; stress urinary incontinence
About This Topic
As we age, mental and physical well-being and health are central to ensuring full participation in a productive, social and happy life. And yet with increased longevity comes increased incidence of incontinence-associated lower urinary and bowel dysfunction, accompanied by the resultant negative individual and societal impacts.
Incontinence is far from benign and its’ negative impact on healthy and active aging manifests in degradation of quality of life, psychosocial well-being and engagement. Regrettably, it is a condition too often perceived as an inevitable reality of the aging process and consequentially has largely gone unnoticed, unrecognized, undertreated and/or marginalized as a health concern. However, as overall life expectancy and the developed world’s senior population increases, it will become an even more common burden on the health care system. Incontinence has tremendous economic impacts in terms of care and support, symptom management, and reductions in economic productivity. Importantly, it is also associated with lack of independent functioning and is often an impetus in the initiation of assisted living and specialized care.
It is hoped that awareness and recognition of the seriousness of incontinence will drive research toward innovations in more effective treatments with fewer or less serious side effects, and could initiate a larger change in current views toward the need for increased diagnosis and treatment, improving the lives of millions of people worldwide.
Manuscript Submission Information
Manuscripts should be submitted through the LIDSEN Submission System. Detailed information on manuscript preparation and submission is available in the Instructions for Authors. All submitted articles will be thoroughly refereed through a single-blind peer-review process and will be processed following the Editorial Process and Quality Control policy. Upon acceptance, the article will be immediately published in a regular issue of the journal and will be listed together on the special issue website, with a label that the article belongs to the Special Issue. LIDSEN distributes articles under the Creative Commons Attribution (CC BY 4.0) License in an open-access model. The authors own the copyright to the article, and the article can be free to access, distribute, and reuse provided that the original work is correctly cited.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). Research articles and review articles are highly invited. Authors are encouraged to send the tentative title and abstract of the planned paper to the Editorial Office (geriatrics@lidsen.com) for record. If you have any questions, please do not hesitate to contact the Editorial Office.
Welcome your submission!
Publication
Screening and Treating Urinary Incontinence in Primary Care: A Missed OpportunityAbstract More than 60% of adult women in the United States have urinary incontinence (UI), with the prevalence increasing to over 80% in women over age 65. Despite its high prevalence, most patients do not seek care and few clinicians screen for UI. The Medicare Health Outcomes Survey queries patients about satisfaction with their provider’s discussi [...] |
Mixed Urinary Incontinence: Diagnosis and ManagementAbstract The evaluation and treatment of mixed urinary incontinence receives relatively little attention as compared to other forms of incontinence. Mixed incontinence, however, defined as the combination of stress and urgency incontinence, accounts for the largest proportion of incontinence, with an increased incidence in older women. The condition [...] |
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