by Shourjo Chakravorty  and Ashka Patel

Received: 21 November 2023;  Published: 10 May 2024;  doi: 10.21926/obm.transplant.2402215

Transplanted lung allografts are particularly susceptible to infection among SOT due to the constant exposure to the environment, aggressive immunosuppressive strategies, and impaired clearance mechanisms after denervation of the transplanted lung. Though prophylactic antimicrobial, antifungal, and antiviral regimens are used as preventive strategies to mitigate the risk of infection, complications related to allograft infection remain one of the primary causes of morbidity and mortality after lung transplantation. [...]

by Leonel Pereira  and Ana Valado

Received: 06 March 2024;  Published: 10 May 2024;  doi: 10.21926/obm.neurobiol.2402223

This review explores the potential of compounds derived from red algae (Rhodophyta) as promising neuroprotective agents for treating neurodegenerative disorders. Red algae, abundant in marine environments, contain bioactive compounds with diverse chemical structures and functionalities. Sulfated polysaccharides, primarily agar and carrageenans, stand out as the predominant and widely utilized compounds derived from red algae. Additionally, red algae harbor a spectrum of potential molecules such as essential fatty a [...]

by Shashya Wijesinghe  and Elizabeta B. Mukaetova-Ladinska

Received: 03 March 2024;  Published: 10 May 2024;  doi: 10.21926/obm.geriatr.2402279

In the UK, 25,000 people from ethnic minority background live with dementia. Although dementia associated risk factors are common amongst South Asians, they tend to present at services later and when in crisis. This review explores UK South Asian communities perception of dementia to understand factors impacting their decision to seek help. Search terms assisted by the PICO strategy were inputted into five databases and ten qualitative papers identified. Meta-ethnography methodological framework was implemented for [...]

by Amanda Pong  and Pavel Klein

Received: 15 February 2024;  Published: 08 May 2024;  doi: 10.21926/obm.genet.2402234

Tuberous sclerosis complex (TSC) is caused by mutations of hamartin (TSC1) or tuberin (TSC2) resulting in disinhibition of the mTOR pathway of cellular proliferation and differentiation and severe neurocognitive impairment, intractable epilepsy and tumors. Epilepsy develops in ~90% folllowed by drug-resistant epilepsy (DRE). Recently, prevention of DRE and developmental encephalopathy was shown to be possible in TSC using early administration of vigabatrin. For the first time, medical treatment successfully prevent [...]

by Justin Cole  , Eugene Golts  , Michael Bernales  , Dina Shirazi  , Deepa Kurup  , Sarah Golts  , Gordon Yung  , Aarya Kafi  , Christine M. Lin  , Travis Pollema  and Kamyar Afshar

Received: 19 October 2023;  Published: 08 May 2024;  doi: 10.21926/obm.transplant.2402214

Despite the concerted efforts by lung transplant recipients (LTR) and their medical teams, hospital readmissions are common in the first year following transplantation. Reasons for unplanned readmissions include allograft rejection, infections, and respiratory failure before the SARS-COV-2 pandemic. Clinical predictors of readmissions have changed over time with the higher risk factors of acceptable criteria for recipients and donors. We aimed to assess more recent readmission rates based on group classifications t [...]

by Shisir Ruwali  , Bharana Ashen Fernando  , Shawhin Talebi  , Lakitha Wijeratne  , John Waczak  , Prabuddha M. H. Madusanka  , David J. Lary  , John Sadler  , Tatiana Lary  , Matthew Lary  and Adam Aker

Received: 19 December 2023;  Published: 08 May 2024;  doi: 10.21926/aeer.2402011

Breathing clean air is crucial for maintaining good human health. The air we inhale can significantly impact our physical and mental well-being, influenced by parameters such as particulate matter and gases (e.g. carbon dioxide, carbon monoxide, and nitrogen dioxide). Building on previous research that explored the effects of particulate matter (PM) in specific environments, analyzed using biometric indicators and machine learning models; this work focuses on the effects and estimation of inhaled nitrogen dioxide ( [...]

by Nadia A. Abdelmegeed Abdelwahed

Received: 08 January 2024;  Published: 06 May 2024;  doi: 10.21926/obm.neurobiol.2402222

In the present era, a healthy life is a challenge for everyone. Therefore, diverting individuals' minds towards physical activity and exercise is necessary for the day. This paper proposes to inspect the impact of physical activity on the development of intention to exercise (ITE) among entrepreneurs. The quantitative study collected data from 383 Egyptian entrepreneurs through a survey questionnaire. Most respondents were males (n = 257 or 67.10%) against females (n = 126 or 32.90%). The range of age of the respon [...]

by Jihyun Cho  , Hojun Lee  , Sang Hee Park  , Myoung Haw Kim  and Seunghee Won

Received: 25 February 2024;  Published: 06 May 2024;  doi: 10.21926/obm.neurobiol.2402221

This study conducted an in-depth analysis of the psychological states of teachers during the first outbreak of coronavirus disease 2019 (COVID-19) using data on school mental health projects related to COVID-19 in Daegu from May to June 2020. The participants comprised 811 (34.9%) male and 1,511 (65.1%) female teachers in 1,041 (44.8%) middle and 1,281 (55.2%) high schools. After schools reopened, the most common causes of unbearable stress were unusual experiences, fear of infection, and negative emotions. Moreove [...]

by Kianoush Hatami Dehnou  and Mohammad Jafar Hadianfard

Received: 14 December 2023;  Published: 03 May 2024;  doi: 10.21926/rpm.2402011

The use of silicone rubber as an implant is limited due to its weak properties. In this study, the impact of various reinforcements, such as TiO2 or SiO2 nanoparticles, carbon, or polypropylene fiber micro reinforcements, on the mechanical, thermal, and viscoelastic properties of silicone rubber composites with RTV-4125 matrix was investigated. The composites were evaluated through several tests, including tensile, compression, FTIR, TGA, DMTA, and water adsorption tests. It was found that the composites' tensi [...]

by Alyssa M. Krueger  , Kelsey Smith  , Arielle Pollock  , Christine Dunkel Schetter  and Nicole E. Mahrer

Received: 24 December 2023;  Published: 30 April 2024;  doi: 10.21926/obm.icm.2402025

Residential and nonresidential fathers are taking an increasingly greater role in their children’s lives, and father involvement predicts positive child outcomes across development. This study utilized data from a large sample of racially and ethnically diverse fathers of low to middle income (n = 1,112) to test if paternal stress is associated with lower father involvement in early infancy and whether perceived social support is protective. Exploratory analyses examined whether the effects of stress on father invo [...]