by Maria Lúcia dos Santos  , Ana Cristina Monteiro  , Andréa Nascimento  , Sívia Barbosa  , Artur Delgado  and Patrícia Zamberlan

Received: 11 April 2024;  Published: 17 July 2024;  doi: 10.21926/rpn.2403010

Epidermolysis Bullosa (EB) is a rare genetic disorder characterized by fragile skin that blisters and tears easily, leading to significant morbidity and mortality. Depending on the specific genetic mutations and the proteins involved, EB can be classified into several subtypes whose molecular complexity is compounded by the variability in mutation types (missense, nonsense, insertions, deletions), their locations within the genes, and the resultant effects on protein function. This systematic review aimed to identi [...]

by Assohoun Fulgence Kraidy  , Islam M. El Radaf  , Andreas Zeinert  , Abdelilah Lahmar  , Aime Pelaiz-Barranco  , Pardis Simon  and Yaovi Gagou

Received: 29 March 2024;  Published: 17 July 2024;  doi: 10.21926/jept.2403013

In this study, tin antimony sulfide (SnSb2S5) thin films with 200 nm, 312 nm, and 431 nm thicknesses were successfully fabricated using thermal evaporation. These films' structural, optical, and photoanode properties were meticulously characterized to assess their suitability for photovoltaic applications. X-ray diffraction (XRD) analysis confirmed the presence of an orthorhombic symmetry phase within the Pnma space group, ensuring the crystalline quality of the films. Raman spectroscopy further validated the cryst [...]

by Mélanie Couture  , Julien Gauthier-Mongeon  , Pearce Simamonika  , Rosalie Bernard  , Kevin St-Martin  , Rosalie Lacasse  and Sarita Israel

Received: 18 December 2023;  Published: 17 July 2024;  doi: 10.21926/obm.geriatr.2403282

Research indicates that adults in the context of gender and sexual diversity (GSD) experienced more violence and discrimination than the rest of the population. GSD refers to all the diversities of sexual characteristics, sexual orientations and gender identity of a person or a group. To encourage the use of evidence-based interventions in health and social services, it is important to extrapolate from the scientific literature how mistreatment situations are managed in this context. A scoping review was conducted [...]

by Havva Özgen Eyüpoğlu  , Erol Eyüpoğlu  and Nedime Serakinci

Received: 13 March 2024;  Published: 17 July 2024;  doi: 10.21926/obm.genet.2403252

Pancreatic damage and pancreatic cancer pose significant challenges due to their complex pathogenesis, limited treatment options, and poor prognosis. In recent years, the potential use of human Mesenchymal Stem Cells (hMSCs) has been explored to address these complex pancreatic conditions and develop novel therapeutics. hMSCs, known for their regenerative and immunomodulatory properties, offer a novel therapeutic avenue for repairing damaged tissues and possibly inhibiting cancer progression. This communication dis [...]

by Roberto Anaya-Prado  , Ana P. Cárdenas-Fregoso  , Ana M. Reyes-Perez  , Danielle M. Ortiz-Hernandez  , Montserrat Quijano-Ortiz  , Monica V. Delgado-Martinez  , Ana S. Pelayo-Romo  , Roberto Anaya-Fernández  , Michelle M. Anaya-Fernández  , Consuelo C. Azcona-Ramirez  , Ivan F. Garcia-Ramirez  , Miguel A. Guerrero-Palomera  , Daniel Gonzalez-Martinez  , Citlalli S. Guerrero-Palomera  , Karina Paredes-Paredes  and Claudia Garcia-Perez

Received: 23 February 2024;  Published: 16 July 2024;  doi: 10.21926/obm.neurobiol.2403232

The human gastrointestinal (GI) tract harbors many microorganisms, including viruses, protozoa, archaea, fungi, and bacteria. Altogether, these microbes constitute what we know as the gut microbiome (GM). These commensal communities have important implications for human health. They influence physiological processes through different mechanisms, including synthesizing neurotransmitters, regulating enzymatic pathways, and releasing molecules responsible for different signal pathways. The interaction between GM and b [...]

by Ioannis Syros  and Xenia Anastassiou-Hadjicharalambous

Received: 19 October 2023;  Published: 15 July 2024;  doi: 10.21926/obm.neurobiol.2403231

Obsessive-Compulsive Disorder (OCD) is a prevalent child and adolescent psychiatric condition characterized by substantial functional impairments. Cognitive Behavioral Therapy (CBT) has emerged as the primary therapeutic approach for managing mild to moderate cases of OCD in children and adolescents. Significant advancements have been made in applying CBT specifically to this age group in the past decade. Exposure and response prevention (ERP) is a core therapeutic technique grounded in the principle that anxiety t [...]

by Eli Cwinn  and Kayla Hamel

Received: 22 January 2024;  Published: 10 July 2024;  doi: 10.21926/obm.icm.2403041

This paper argues that psychology, as a discipline, requires research to be situated in the context of a content-based theory. We identify several problems and pitfalls with requiring a content-based theory for applied mental health research, a priori. Nonetheless, we also articulate a rationale for why theory matters and that a new sort of theoretical framework is required for applied mental health research. We address this need by articulating a new theoretical framework called Applied Pragmatic Functional Contex [...]

by Koré Monsterrat Moreno-Calderón  , Alfredo Saavedra-Molina  , Mariana Gómez-Barroso  , Donovan Javier Peña-Montes  , Christian Cortés-Rojo  , Alain R. Rodríguez-Orozco  , Omar Ortiz-Ayala  and Rocío Montoya-Pérez

Received: 08 January 2024;  Published: 10 July 2024;  doi: 10.21926/obm.icm.2403040

An excess of adipose tissue characterizes obesity; it is associated with complications such as diabetes and cardiovascular diseases due to an alteration in the lipid profile; this condition affects all tissues; even skeletal muscle is the most affected, causing its malfunction and bringing more significant consequences. Exercise has been described as one of the best treatments to combat obesity. At the same time, E. carlinae is a plant proven to have lipid-lowering and hypoglycemic effects, improving the function o [...]

by Giuseppe Merra

Received: 03 July 2024;  Published: 10 July 2024;  doi: 10.21926/obm.genet.2403251

by Anna Passaro  , Antonio Zullo  , Mariacarla Di Gioia  , Enza Curcio  and Fabrizio Stasolla

Received: 27 January 2024;  Published: 05 July 2024;  doi: 10.21926/obm.genet.2403250

Rett syndrome (RTT) is a rare neurodevelopmental disorder primarily affecting females, characterized by a spectrum of debilitating symptoms that impact neurological, cognitive, and motor functions. Eye-tracking technology (ETT) has emerged as a prominent tool in Augmentative and Alternative Communication (AAC) systems, particularly for neurological patients with motor and verbal impairments. This narrative review aimed to evaluate studies conducted on the use of ETT to improve cognitive abilities in girls with RTT [...]