by Lúcia Bacalhau  and Patrícia Pontífice-Sousa

Received: 19 September 2024;  Published: 06 February 2025;  doi: 10.21926/obm.transplant.2501233

Allogeneic Stem Cells Transplantation (ASCT) and, consequently, the chronicity associated with this life event has a growing prevalence and a significant impact on the life and daily life of each person who experiences it. The growing number of ASCT survivors highlights the need to reflect on the unique challenges they face throughout their recovery. To understand the meaning of the encounter with time in the lived experience of comfort for survivors of ASCT. Qualitative approach using van Manen's phenomenology of [...]

by Leonard A. Jason

Received: 15 October 2024;  Published: 05 February 2025;  doi: 10.21926/obm.neurobiol.2501267

Following mental or physical exertion, patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) experience Post-Exertional Malaise (PEM). Although self-report questions represent less expensive and invasive procedures to assess PEM, variability in the wording of the symptom can cause reliability and validity problems. If different PEM measures are used in studies, this could create difficulties in replicating findings, identifying biomarkers, and determining effective treatments for patients. The o [...]

by Nydia Rena Benita Sihombing  , Nani Maharani  , Agustini Utari  and Tri Indah Winarni

Received: 29 November 2024;  Published: 05 February 2025;  doi: 10.21926/obm.genet.2501284

Deletion of chromosome 1p36 encompassed various genes; however, the role of the CAMTA1 gene in the 1p36 region is less investigated. We report a child with developmental delay, a history of congenital heart abnormality, self-injurious behavior, nystagmus, and facial dysmorphism. Chromosomal microarray revealed a 257.2 kb deletion of chromosome 1p36.31, with CAMTA1 as the only involved gene. We explore overlapping clinical features of both chromosome 1p36 deletion and CAMTA1 intragenic deletion, including intellectu [...]

by Fatimazahra Smaili  , Khawla Zerrouki  , Fatima Ezzahra Aouni  , Ayad Ghanam  , Maria Rkain  , Abdeladim Babakhouya  and Mariam Tajir

Received: 04 October 2024;  Published: 04 February 2025;  doi: 10.21926/obm.genet.2501283

Dystrophinopathies are genetic muscular disorders with recessive inheritance linked to the X chromosome due to mutations in the dystrophin gene, the DMD gene located in Xp21. The best-known forms are Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD). Our study aims to determine the molecular profile and genotype/phenotype correlations of dystrophinopathies in the eastern region of Morocco. We report patients referred for 4 years (2020-2023) to the Medical Genetics Laboratory of the Mohammed VI U [...]

by Christopher Igwe Idumah  , Ifeanyi Emmanuel Okoye  and Chioma Joan Ikebudu

Received: 05 September 2024;  Published: 02 February 2025;  doi: 10.21926/rpm.2501005

3-Dimension printing (3-DPT) or additive manufacturing (AM) technology has been utilized for a while in the construction of customized 3-D objects utilizing computer software such as computer-aided design (CAD). However, the emergence of an innovative and new four-dimensional printing (4-DPT) has enabled the synergy of AM technology with programmable materials in transforming digital processes virtually into physical entities, thereby providing innovation and advanced functionalities. 4-DPT is a procedure facilitat [...]

by Anita Padmanabhanunni  and Tyrone Pretorius

Received: 21 September 2024;  Published: 27 January 2025;  doi: 10.21926/obm.neurobiol.2501266

Generalized Anxiety Disorder (GAD) is a prevalent mental health condition and the GAD-7 is widely used as a screening tool and measure of GAD severity. However, research has yielded conflicting findings regarding the factor structure of the instrument, with some studies supporting a unidimensional interpretation while others suggest a two-factor solution. These inconsistencies highlight the importance of validating the GAD-7 across diverse populations. This study aimed to assess the psychometric properties and fact [...]

by Hicham Bouchahta  , Zhour EL Amrani  , Siham Chafai Elalaoui  , Fatima Ouboukss  , Aziza Sbiti  , Laila Sbabou  , Thomas Liehr  , Abdelaziz Sefiani  and Abdelhafid Natiq

Received: 14 October 2024;  Published: 27 January 2025;  doi: 10.21926/obm.genet.2501282

Cat-eye syndrome (CES) is a rare genetic disease first reported in 1965. The estimated prevalence of CES is 1:50,000 to 1:150,000, and it is typically associated with an inverted duplicated small supernumerary marker chromosome (sSMC) derived from chromosome 22. The specific chromosomal band involved in CES causing partial tetrasomy is 22q11.21, where chromosomal rearrangements occur due to the presence of low-copy repeats (LCR22). The phenotype of CES is extremely diverse, ranging from normal to multiple abnormali [...]

by Yusuf Sani  , Raba’ah Syahidah Azis  , Ismayadi Ismail  , Yazid Yaakob  , Chen Soo Kien  , Mohd Mustafa Awang Kechik  and Lim Kean Pah

Received: 11 October 2024;  Published: 26 January 2025;  doi: 10.21926/rpm.2501003

The widespread usage of various wireless equipment in many facets of life has significantly contributed to the severe pollution caused by electromagnetic radiation. Thankfully, scientists have created materials that can absorb microwave radiation and convert dangerous electromagnetic waves into other forms of energy, including heat energy. Many recent investigations have been published regarding developing materials that absorb microwaves with different constituents, morphologies, and architectures. Microwave-absor [...]

by Cheryl Armstrong  , Katarina Friberg-Felsted  , Jennifer Macali  , Jennifer Clifton  and Sara E. Simonsen

Received: 02 July 2024;  Published: 26 January 2025;  doi: 10.21926/obm.icm.2501008

The COVID-19 pandemic presented major changes for individuals working in nursing academia. While university faculty and staff encountered many challenges, the pandemic also presented new opportunities. The purpose of this study was to determine how the early months of the COVID-19 pandemic impacted nursing faculty and staff perceptions about their wellness experiences. An on-line survey was developed and sent to all faculty and staff. Data were collected through a convenience sample using both open-ended and closed [...]

by Despina Vamvuka  , Stelios Sfakiotakis  and Elpida Patlaka

Received: 12 November 2024;  Published: 24 January 2025;  doi: 10.21926/jept.2501004

Independent parallel reactions (IPR) and distributed activation energy (DAEM) kinetic models were developed and compared for the combined pyrolysis-gasification of two agro-industrial waste materials. The aim was to recycle greenhouse gas carbon dioxide for mitigating emissions, to evaluate the thermal behavior, reactivity, conversion and product composition in terms of structural/chemical characteristics of the fuels, and to provide accurate kinetic parameters useful in the scaling-up of the process. The experimen [...]