by Stephen Ames

Received: 08 April 2019;  Published: 13 August 2019;  doi: 10.21926/obm.geriatr.1903068

Thirty years ago, Tom Kitwood proposed a change in the care of people with dementia, from ‘warehousing’ to ‘person-centred care’. The change had noticeable benefits for those with dementia. Kitwood set out his presuppositions for this change. For example, Kitwood understood personhood as the standing or status bestowed on one human being by others in the context of relationships and social being and held that respect for the absolute value of each person is a key theme in Western ethical discourse. He was clear thi [...]

by Shira Peleg  and Howard Litwin

Received: 23 March 2019;  Published: 12 August 2019;  doi: 10.21926/obm.geriatr.1903067

Background: Differential effects of the characteristics of social network on limitations with activities (LWA) and the quality of life (QOL) among older adults, and the moderating role of depression were studied. Methods: The data obtained from two consecutive waves of the Survey of Health, Aging, and Retirement in Europe (SHARE) was examined. Results: Emotional closeness, satisfaction with the social network, and contact frequency were able to predict the QOL and not LWA. Moreover, depression was observed to moder [...]

by Rachel Rutherford  and Patrick B Allen

Received: 25 February 2019;  Published: 12 August 2019;  doi: 10.21926/obm.hg.1903031

Crohn's Disease (CD) is a chronic inflammatory, relapsing and remitting condition that leads to structural damage of the bowel wall. It can be located in any part of the gastrointestinal tract with associated extra-intestinal manifestations. It varies in severity having many complications resulting in significant morbidity. In the past decade medical management of CD has evolved rapidly and with ongoing research it continues to show promising novel therapies. In this article we aim to give an overview of current li [...]

by Ilaria Scarpelli  , Fabienne Marcelli  , Francesca Mattioli  and Jacqueline Schoumans

Received: 01 April 2019;  Published: 09 August 2019;  doi: 10.21926/obm.genet.1903088

With the advent of next-generation sequencing (NGS), genomic profiling of tumors has been gradually introduced into the clinical setting and has become a standard in cancer care. NGS allows convenient, rapid, and inexpensive sequencing and the commercially available NGS panels enable the detection of single or global genomic alterations of germline and somatic origin. Today, genomic mutation profiling using NGS is indispensable for disease evaluation and prediction of prognosis or responsiveness to cancer therapy. [...]

by Garuth Chalfont  , Jane Simpson  , Sarah Davies  , David Morris  , Ruth Wilde  , Leigh Willoughby  and Christine Milligan

Received: 08 April 2019;  Published: 07 August 2019;  doi: 10.21926/obm.geriatr.1903066

The dominant narrative around dementia argues that progression cannot be halted or reversed. However, evidence on multimodal non-pharmacological treatments formulated around a ‘personalised medicine’ approach challenges this view. This paper reviews the current evidence for dementia prevention utilising such treatments and explains the logic of applying personalised medicine. The functional medicine treatment approach to ‘root cause’ analysis is presented as currently practiced with patients experiencing cognitive [...]

by Hsueh-Fen S. Kao  and Maria A. Amaya

Received: 19 May 2019;  Published: 07 August 2019;  doi: 10.21926/obm.geriatr.1903065

Background: In 2016, Hispanic/Latino (H/L) Americans made up 8% of the older population (≥65) and 22.9% of the oldest population (≥85) in the United States. It is projected that the older H/L population will grow to 21% by 2060. Currently the older H/L population depends primarily on their families for care. Methods: Review published caregiving models for older adults in H/L populations. Results: Gradual and inevitable acculturation of H/L caregivers to U.S. social customs, and the mutual relationship within the [...]

by Patricia Lynn Dobkin

Received: 14 May 2019;  Published: 07 August 2019;  doi: 10.21926/obm.icm.1903050

The author writes a genuine story using a narrative medicine writing style [1]. She relates how she applied mindfulness awareness and meditation practices to accompany her best friend, Abigail (Abigail is a pseudonym), who struggled through stages 3 and 4 breast cancer, including its noxious treatments and upsetting side effects. Clinical practice can be enhanced with narrative competence in that it helps the author recognize, interpret and be touched by patients’ stories, including all aspects of illness experienc [...]

by Babkir Ali

Received: 30 May 2019;  Published: 07 August 2019;  doi: 10.21926/jept.1903002

The main objective of this paper is to study the sustainability of power generation from an abandoned oil and gas well in the province of Alberta, Canada. Economic and environmental indicators were used for the sustainability assessment. A conceptual design for a pilot plant was developed, and the main parameters were determined. An abandoned oil and gas well represents the thermal power source through circulating water into an organic Rankine cycle (ORC) unit to generate electricity. The thermal power is extracted [...]

by H. Hakemi  , O. Pinshow  and D. Gal-Fuss

Received: 24 June 2019;  Published: 07 August 2019;  doi: 10.21926/rpm.1903002

In the past few years, there have been many attempts to commercialize Polymer Dispersed Liquid Crystal (PDLC) for Rear Projection Screen (RPS) in electrically switchable films and glass products. This application is based on the exceptional image quality of PDLC at a wide viewing angle. However, due to the high price of conventional switchable PDLC privacy glass, the integration of RPS in PDLC failed to attract large multimedia and entertainment markets. An obvious solution to this problem is the independent develo [...]

by Petr A. Fedotov  , Maria A. Simonenko  , Yulia V. Sazonova  , Mariya A. Bortsova  , Artem N. Kostomarov  and Mariya Yu. Sitnikova

Received: 01 February 2019;  Published: 05 August 2019;  doi: 10.21926/obm.transplant.1903077

Background: To estimate the survival of patients in the heart transplantation waiting list (HTx WL) at Almazov National Medical Research Centre (V.A. Almazov NMRC), Saint-Petersburg, Russia, from 2010 to 2017 and to define risk factors for death among these patients. Methods: It was a single-center retrospective study involving 151 patients with advanced chronic heart failure (CHF) in the HTx WL. Results: Mortality in the HTx WL for the period 2010-2017 was found to decrease. Based on the results of constructing th [...]