by Habibur P. Rahman  , DaiRicky H Bhogal  and Patricia F. Lalor

Received: 05 February 2018;  Published: 16 May 2018;  doi: 10.21926/obm.hg.1802007

Background & Aims. Acute kidney injury (AKI) is a serious complication of liver surgery and associated with significant morbidity and mortality. The incidence of AKI following hepatic surgery can be as high as 94%, with highest rates seen following orthotopic liver transplantation, particularly when extended criteria grafts are used. Strategies to identify patients at risk of AKI may enable early interventions to prevent or minimise AKI. Methods. A systematic review was conducted using PubMed, Medline, Cochrane and [...]

by Hidehiro Kamezaki  , Dai Sakamoto  , Daiki Okamura  , Koji Nakagawa  and Naoya Kato

Received: 10 December 2017;  Published: 14 March 2018;  doi: 10.21926/obm.hg.1801006

(1) Background: Endoscopy has become the primary diagnostic and treatment technique for non-variceal upper gastrointestinal bleeding. Despite advancements in therapeutic methods and instrumentation, endoscopic hemostatic failure occurs in 10% of patients. This study aimed to analyze endoscopic findings in patients with failed hemostasis and to elucidate strategies for endoscopists and gastroenterologists to facilitate improved treatment outcomes. (2) Methods: A total of 128 patients received hemostatic treatment fo [...]

by Tatsuo+ Kanda  , Shunichi Matsuoka  and Mitsuhiko Moriyama

Received: 18 October 2017;  Published: 29 October 2017;  doi: 10.21926/obm.hg.1704005

(This is review and no abstract)

by Koji Takahashi  , Tatsuo Kanda  , Yuki Haga  , Reina Sasaki  , Masato Nakamura  , Shuang Wu  , Shin Yasui  , Hidehiro Kamezaki  and Osamu Yokosuka

Received: 23 June 2017;  Published: 27 July 2017;  doi: 10.21926/obm.hg.1703004

(1) Background: Infection with hepatitis B virus (HBV) infection during pregnancy occasionally raises concerns, including acute exacerbation and the potential for mother-to-child transmission. (2) Case Report: Here, we present a case of a female patient with a chronic HBV infection who was treated with tenofovir disoproxil fumarate (TDF) and had a normal pregnancy and delivery. Furthermore, the use of TDF, HBV vaccination and passive immunization of her child with hyperimmune hepatitis B immunoglobulin successfully [...]

by Tomomi Kogiso  , Mutsuki Kobayashi  , Kuniko Yamamoto  , Yuichi Ikarashi  , Kazuhisa Kodama  , Makiko Taniai  , Nobuyuki Torii  , Kazunari Tanabe  , Hideki Ishida  , Shohei Fuchinoue  , Hiroto Egawa  , Masakazu Yamamoto  , Etsuko Hashimoto  and Katsutoshi Tokushige

Received: 08 February 2017;  Published: 06 April 2017;  doi: 10.21926/obm.hg.1702003

Background: Hepatitis C virus (HCV) infection frequently occurs in recipients of liver or kidney transplants (LT/KT). Interferon (IFN)-based therapies are used to treat HCV, but their efficacy is low. Methods: We report 24 patients who received HCV therapy after LT/KT. Design, Setting, and Participants-Twelve LT and 12 KT recipients (median age, 59 years; 15 males; 21 serological type 1) were enrolled, of whom eight (six with LT) were treated with IFN-based therapy. Twelve received direct-acting antiviral drugs [ [...]

by Tatsuo Kanda  and Osamu Yokosuka

Received: 22 January 2017;  Published: 03 February 2017;  doi: 10.21926/obm.hg.1701002

by Hidehiro Kamezaki  , Tatsuo Kanda  , Osamu Yokosuka  , Yasunori Kasahara  and Takayuki Sakurai

Received: 16 November 2016;  Published: 21 January 2017;  doi: 10.21926/obm.hg.1701001

(1) Background: Preventative treatment for Pneumocystis jirovecii pneumonia (PCP) has been recommended for patients receiving ≥20 mg/day prednisolone. We describe a patient who developed PCP while receiving a dose of 15 mg/day prednisolone, and consider criteria for the initiation of preventative therapy for PCP in patients with autoimmune hepatitis (AIH) treated with prednisolone. (2) Case Report: A 71-year-old woman initially possessed dark-colored urine, white stool, and decreased appetite, which indicated hepat [...]

by Bubacar Embaló  , Jhenyfer Amanda Ciriaco Canhete  , Gabriel Schmitt da Cruz  , Daniela de Rossi Figueiredo  , Heloisa Godoi  and Ana Lúcia Schaefer Ferreira de Mello

Received: 30 October 2025;  Published: 19 August 2026;  doi: 10.21926/obm.geriatr.2603341

The study aimed to understand the provision of home dental care for homebound older adults within the context of primary healthcare. A mixed-methods, concurrent, parallel, and cross-sectional study was conducted. Quantitative data were collected from 123 homebound older adults through structured questionnaires and oral examinations and analyzed using descriptive and bivariate statistics. Qualitative data were collected through interviews with 37 homebound older adults and/or caregivers and eight primary healthcare [...]

by Paolo Giacomoni  and Pier Francesco Morganti

Received: 05 January 2026;  Published: 23 July 2026;  doi: 10.21926/obm.geriatr.2603340

Aging is defined as the accumulation of damage, and several factors have been recognized as “factors of aging”. A sensible holistic approach is appropriate to reduce the rate of accumulation of damage, while maintaining the well-being of the individual. The holistic approach of L-Raphael defines seven fields of intervention: Outdoor management, Physical management, Medical management, Nutritional management, Stress management, Aesthetic management, and Leisure management. These interventions apply to skin aging as [...]

by Cassandra R. Hatt  , Aaron M. Eakman  and Allison A. M. Bielak

Received: 17 December 2025;  Published: 09 June 2026;  doi: 10.21926/obm.geriatr.2602339

Multiple theories from the psychological and occupational therapy sciences suggest that there may be reciprocity between activity selection and the meanings we draw from them. As such, meaningfulness may be an important contextual mechanism through which activity engagement positively influences cognition, but no research has examined these links in healthy middle-aged and older adults. This study examined the predictive ordering of the associations between activity engagement, meaningfulness, and cognition. Eighty [...]