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Special Issue

Epigenetic Mechanisms in Health and Disease

Submission Deadline: May 31, 2018 (Open)               Submit Now

Guest Editors

Stéphane Viville, PhD
Professor, LABORATOIRE DE DIAGNOSTIC GENETIQUE, UF3472 – Infertilité, Nouvel Hôpital Civil,
1 place de l’Hôpital, 67091 Strasbourg cedex, France
E-Mail: [email protected]
Website:  http://med.unistra.fr/eng/Recherche/Liste-des-Hospitalo-Universitaires/VIVILLE
Research Interests: human genetics of infertility; male and female infertility; human gametogenesis; human infertility and epigenetics; embryonic stem cells

Marcel Mannens, PhD
Professor, Department of Clinical Genetics, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands
E-Mails: [email protected]; [email protected]
Website: https://www.amc.nl/web/research-75/person-1/prof.-dr.-m.m.a.m.-mannens.htm
Research Interests: genome diagnostics; epigenetics of disease; cardiogenetics

Publication

Review

Redirecting Fetal Programming: Evidence of Interventions that May Be A Tool for Health

Camila Sandoval, Colleen A Lambo, Michael Carey Satterfield
Received: June 1, 2018; Published: December 28, 2018; doi:10.21926/obm.genet.1804058

Review

Distinct Mechanisms of Alterations in DNA Methylation/Demethylation Leading to Myelodysplastic Syndromes/Acute Myeloid Leukemia and Chronic Lymphocytic Leukemia

Cristina Bagacean, Anne Bordron, Tempescul Adrian, Jean Christophe Ianotto, Gaelle Guillerm, Wesley H Brooks, Marie-Anne Couturier, Mihnea Zdrenghea, Christian Berthou, Yves Renaudineau
Received: June 5, 2018; Published: December 14, 2018; doi:10.21926/obm.genet.1804054

Original Research

Evaluation of Classical Statistical Methods for Analyzing BS-Seq Data

Hengrui Luo, Shili Lin
Received: May 23, 2018; Published: December 10, 2018; doi:10.21926/obm.genet.1804053

Review

Epigenetics and Infectious Disease: State-of-the-Art and Perspectives in New Generation Therapies

Maddaloni Valeria, D’Arco Daniela, Morano Francesca, Pepe Nicola, Atripaldi Luigi
Received: May 30, 2018; Published: November 12, 2018; doi:10.21926/obm.genet.1804048

Review

Epigenetic Regulation by Androgen Receptor in Prostate Cancer

Ken-ichi Takayama
Received: May 26, 2018; Published: November 2, 2018; doi:10.21926/obm.genet.1804047

Original Research

The Induction of Histone H3K4 Methylation on the SI Gene Correlates with SI mRNA Levels in Enterocyte-Like Caco-2 Cells

Kazuki Mochizuki, Ayumi Osaki, Yuko Inamochi, Toshinao Goda
Received: December 18, 2017; Published: October 30, 2018; doi:10.21926/obm.genet.1804046

Original Research

Evaluation of Recent Statistical Methods for Detecting Differential Methylation Using BS-seq Data

Chenggong Han, Hancong Tang, Shuyuan Lou, Yuan Gao, Min Ho Cho, Shili Lin
Received: May 23, 2018; Published: October 15, 2018; doi:10.21926/obm.genet.1804041

Review

Deciphering the Epigenetic Landscape of Suicidal Behaviour: A Review of Current Findings, Caveats and Future Directions

Stefania Policicchio, Emma L Dempster, Therese M Murphy
Received: June 20, 2018; Published: October 6, 2018; doi:10.21926/obm.genet.1804039

Review

Histone O-GlcNAcylation and Potential Biological Functions

Mitsuko Hirosawa, Koji Hayakawa, Kunio Shiota, Satoshi Tanaka
Received: July 5, 2018; Published: September 19, 2018; doi:10.21926/obm.genet.1803036

Review

Epigenetics of IgA Nephropathy: A Brief Review

Stamatia Stai
Received: May 27, 2018; Published: September 7, 2018; doi:10.21926/obm.genet.1803032

Review

Uniparental Disomy and Imprinting Disorders

Thomas Eggermann, Deborah J.G. Mackay, Zeynep Tümer
Received: June 28, 2018; Published: August 30, 2018; doi:10.21926/obm.genet.1803031

Original Research

New Insights into the Epigenetic Activities of Natural Compounds

Melita Vidakovic, Jessica Marinello, Maija Lahtela-Kakkonen, Daumantas Matulis, Vaida Linkuvienė, Benoît Y. Michel, Ruta Navakauskienė, Michael S. Christodoulou, Danielle Passarella, Saulius Klimasauskas, Christophe Blanquart, Muriel Cuendet, Judit Ovadi, Stéphane Poulain, Fabien Fontaine-Vive, Alain Burger, Nadine Martinet
Received: May 30, 2018; Published: August 16, 2018; doi:10.21926/obm.genet.1803029

Opinion

Runs of Homozygosity and Epigenetic Deregulation of Genomic Imprinting

Ivan Y. Iourov, Svetlana G. Vorsanova, Yuri B. Yurov
Received: May 29, 2018; Published: August 15, 2018; doi:10.21926/obm.genet.1803028

Original Research

Epigenetic Symmetry of DLGAP2: Pre-Implantation Maternal Methylation Switches to a Random Monoallelic Profile in Somatic Tissues

Ana Monteagudo-Sánchez, Marta Sánchez-Delgado, Sonia Guara Ciurana, Jose Medrano, Maria Eugenia Poo-Llanillo, Miho Ishida, Gudrun E. Moore, Isabel Iglesias-Platas, Carlos Simón, David Monk
Received: May 29, 2018; Published: July 30, 2018; doi:10.21926/obm.genet.1803026

Review

Non-Coding RNAs in Cutaneous Melanoma Development, Progression and Dissemination

Virginie Vignard, Delphine Fradin
Received: March 13, 2018; Published: May 16, 2018; doi:10.21926/obm.genet.1802020

Review

Current Understanding of DNA Methylation and Age-related Disease

Eunise M. Aquino, Miles C. Benton, Larisa M. Haupt, Heidi G. Sutherland, Lyn R. Griffiths, Rodney A. Lea
Received: February 12, 2018; Published: April 12, 2018; doi:10.21926/obm.genet.1802016

Review

The Role of Epigenetics in Developmental Programming and the Developmental Origins of Health and Disease

Kazuki Mochizuki, Chihiro Imai, Noriko Sato, Takeo Kubota
Received: June 20, 2017; Published: October 20, 2017; doi:10.21926/obm.genet.1704008