Open Access Review

Curing Alzheimer’s Disease: Myriad Causes and Myriad Cures Await

Mario D. Garrett
Received: June 12, 2019; Published: July 16, 2019; doi:10.21926/obm.geriatr.1903063

Abstract: Simplifying the cause of Alzheimer’s disease has lulled the public into believing that the search for a cure is within reach. The disease has captured the attention of researchers worldwide, catapulting the disease as the third most funded research interest (after cancer and HIV). But after a centur [...]

Open Access Review

Therapeutic Strategies and Current Management for Hepatic Encephalopathy in Liver Cirrhosis

Kazuyuki Suzuki, Akinobu Kato, Yasuhiro Takikawa
Received: February 04, 2019; Published: July 16, 2019; doi:10.21926/obm.hg.1903027

Abstract: Hepatic encephalopathy (HE) is a neuropsychiatric syndrome showing a wide spectrum and one of the serious complications seen in patients with acute and chronic liver disease or spontaneous portal-systemic shunting. Recently, HE has been classified into two categories: covert HE, which involves minim [...]

Open Access Communication

Photobiomodulation Therapy (PBMT) as a Complementary Medicine for Women to Adjust Their Autonomic Nervous Systems and Induce Specific Brain Waves - A Case Report

Jih-Huah Wu
Received: March 04, 2019; Published: July 15, 2019; doi:10.21926/obm.icm.1903046

Abstract: Sleep is very important to maintain the health of physiology and psychology, especially for women. Many studies proved the symptoms of sleep disturbance can cause inflammation, coagulation, insulin resistance and psychosocial distress in women than in men. A lot of medications were used to treat sle [...]

Open Access Review

Role of Artificial Intelligence (AI) Art in Care of Ageing Society: Focus on Dementia

Tracy Harwood, John Maltby, Elizabeta B. Mukaetova-Ladinska
Received: March 28, 2019; Published: July 15, 2019; doi:10.21926/obm.geriatr.1903062

Abstract: Background: Art enhances both physical and mental health wellbeing. The health benefits include reduction in blood pressure, heart rate, pain perception and briefer inpatient stays, as well as improvement of communication skills and self-esteem. In addition to these, people living with dementia bene [...]

Open Access Review

Breath Practices for Survivor and Caregiver Stress, Depression, and Post-traumatic Stress Disorder: Connection, Co-regulation, Compassion

Patricia L. Gerbarg, Richard P. Brown, Chris C. Streeter, Martin Katzman, Monica Vermani   
Received: April 10, 2019; Published: July 12, 2019; doi:10.21926/obm.icm.1903045

Abstract: Does compassion itself benefit the healing process or does the activation of neurophysiological processes, from which the experience of compassion arises, trigger a cascade of physical and psychological changes that support health and well-being? Exploration of the neurological substrates of compass [...]

Open Access Review

Review of Current Evidence in Acute Pancreatitis

Samantha Varley, Kirsten Rossi, Meghan Murray, Alissa Nichole
Received: May 17, 2019; Published: July 12, 2019; doi:10.21926/obm.hg.1903026

Abstract: Acute pancreatitis (AP) is an inflammatory condition of the pancreas and is one of the most common ailments of the gastrointestinal system that results in significant morbidity and mortality. The main etiologic causes of AP are alcohol consumption, gallstones, hypertriglyceridemia, and biliary stone [...]

Open Access Original Research

Genes Coding for GPI Biosynthesis in Pneumocystis Experienced Relaxed Selection: A Follow-up Study

Luis Delaye
Received: May 5, 2019; Published: July 11, 2019; doi:10.21926/obm.genet.1903083

Abstract: Background: Phylogenetic analyses shows that Pneumocystis species have coevolved with their mammalian hosts for millions of years. As a result, infection by Pneumocystis is species specific (i.e. a given Pneumocystis species can infect only a single species of host). This specificity suggests the ex [...]

Open Access Research Article

A Simple and Effective Non-Human Primate Diabetic Model Combining Sub-Total Pancreatectomy and Low-Dose Streptozotocin Injection

Ibrahim Fathi, Takehiro Imura, Kozue Imura, Megumi Goto, Yasuhiro Igarashi, Akiko Inagaki, Makiko Kikkawa, Fumiko Ono, Hiroo Iwata, Yohichi Yasunami, Masafumi Goto
Received: March 27, 2019; Published: July 09, 2019; doi:10.21926/obm.transplant.1903071

Abstract: BACKGROUND. Current non-human primate diabetic models, namely those induced by total pancreatectomy or streptozotocin (STZ) injection, suffer from several disadvantages, including a long surgical procedure, the need for continual digestive enzyme replacement, and a delayed oral intake after total pa [...]

Open Access Original Research

Estimating Potential Cost Containment through Provision of Unplanned Institutional Respite Services to Support Home-Based Care within Japan’s Long-Term Care Insurance System

Yoko Moriyama, Timothy Bolt, Marilyn Luptak, Nanako Tamiya
Received: February 19, 2019; Published: July 09, 2019; doi:10.21926/obm.geriatr.1903061

Abstract: Background: Many informal caregivers providing at-home care to older family members want to continue serving as the primary caregiver if they get sufficient support. A key service enabling continued at-home care is access to unplanned respite care facilities for temporary institutional care on shor [...]

Open Access Commentary

Compassion in Medical Practice

Christopher Lam
Received: April 25, 2019; Published: July 08, 2019; doi:10.21926/obm.icm.1903044

Abstract: Compassion and kindness can be cultivated and enhanced. Over the years in medical practice I have witnessed many healthcare workers, after having worked with kind and caring practitioners, become progressively more humane. Those of us who are teachers need to be mindful of that. In educating new [...]

Open Access Review

Parting with the Concept of Alzheimer’s Disease in Senium

Pavel Kalvach, Martin Vogner
Received: March 30, 2019; Published: July 08, 2019; doi:10.21926/obm.geriatr.1903060

Abstract: Our understanding of the mental deterioration associated with old-age have undergone a number of changes over the past two centuries and have spurred major scientific debates. In the 19th century, this disorder was still considered to be an inevitable feature of aging. The dawn of the 20th century o [...]

Open Access Review

Complementary and Alternative Medicine (CAM) Usage in Breast Cancer

Birthe Osorio, Karsten Münstedt
Received: February 27, 2019; Published: July 05, 2019; doi:10.21926/obm.icm.1903043

Abstract: (1) Background: Especially women with breast cancer look for offers from complementary and alternative medicine for various reasons. Unfortunately, the value of most offer has to be considered unclear. (2) Methods: This review was to identify reasonable strategies for patients with breast cancer bas [...]

Open Access Original Research

Effect of Acute Moderate-Intensity Exercise on Autobiographical Episodic Memory and Semantic Memory

Sierra Day, Paul D. Loprinzi
Received: April 27, 2019; Published: July 04, 2019; doi:10.21926/obm.icm.1903042

Abstract: The objective of this study was to evaluate the effects of acute moderate-intensity exercise on autobiographical episodic memory and semantic memory. A two-arm, parallel-group randomized controlled intervention was employed. The experimental group engaged in an acute bout of treadmill exercise for 1 [...]

Open Access Original Research

Assessing the Impact of a Game-Centered Mobile App on Community-Dwelling Older Adults’ Health Activation

K. Jason Crandall , Matthew Shake, Uta Ziegler
Received: April 11, 2019; Published: July 04, 2019; doi:10.21926/obm.icm.1903041

Abstract: Background: Older adults’ experience normative age-graded declines in physical and cognitive performance and many must manage one or more chronic conditions. Exercise programs can help to improve both their physical health and their knowledge, skill, and confidence in managing aspects of their own h [...]

Open Access Research Article

Daytime Sleepiness and the Well-Being and Academic Attainment of University Students in the UK

Kate Howells, Andrew P. Smith
Received: April 02, 2019; Published: July 02, 2019; doi:10.21926/obm.neurobiol.1903032

Abstract: Background: Previous research suggests that insufficient daily sleep has negative effects on both well-being and academic attainment. Much of the research in this field has focused on adolescents and children rather than university students in the UK. Methods: The present study used the Student Well [...]

Open Access Case Report

Case Series of Multiple Health Benefits in Those Undertaking Extended Qigong Practice as a Complementary Self-care Practice in an Outpatient Pain Clinic

Lauren Curry, Meghan Pike, Mary Lynch, Dana Marcon, Jana Sawynok
Received: April 01, 2019; Published: June 28, 2019; doi:10.21926/obm.icm.1902040

Abstract: Background: Qigong, traditional Chinese mind-body practices, is currently receiving increasing attention with exploration of what it is and what it does. Common elements include postures and movement, attention to breathing, and mental instructions. There is a growing literature on the health benefi [...]

Open Access Research Article

Autonomic Function Correlates with Microflora Compositions in a Small Cohort of Patients with Autism Spectrum Disorder: Preliminary Clinical Data and Discussion

Daniel Goyal, Fatma Mansab, James Neil, Jaleel Miyan
Received: March 05, 2019; Published: June 28, 2019; doi:10.21926/obm.neurobiol.1902031

Abstract: Research into the effects of microflora on health and in disease has increased recently. Such enthusiasm seems well placed. Should the preliminary studies translate through the larger, more powerful studies, the medical community may well have an entirely new platform from which to intervene for h [...]

Open Access Communication

A Neurotransmitter Approach to the Trolley Problem

Daniel Z. Lieberman, Sara Teichholtz, Brenna R. Emery
Received: Feburary 25, 2019; Published: June 28, 2019; doi:10.21926/obm.neurobiol.1902030

Abstract: Is it ethically permissible to sacrifice the life of one human being in order to save the lives of five others? This question forms the basis of the famous thought experiment called “the trolley problem.” Surveys have found that 90 percent of people agree it is permissible when the victim to be sacr [...]

Open Access Review

Nonalcoholic Fatty Liver Disease and Inflammatory Bowel Disease: Complex Interactions, Evaluations, and Management Decisions

Brett Sadowski, Sarah Ordway, Kevin Bobeck, Adam Tritsch, Manish Singla
Received: January 31, 2019; Published: June 28, 2019; doi:10.21926/obm.hg.1902025

Abstract: Diseases of the liver are commonly encountered in patients with Inflammatory Bowel Disease (IBD). While the differential for IBD patients with elevated liver associated enzymes is broad, it is similar to that of the general population. This differential includes including non-alcoholic fatty liver d [...]

Open Access Review

Clinical Tolerance Trials in Renal Transplantation – Where Do We Stand?

Joachim Andrassy, Antje Habicht
Received: November 05, 2018; Published: June 27, 2019; doi:10.21926/obm.transplant.1902070

Abstract: In recent years, the potential of hematopoietic stem cells, regulatory T-cells and mesenchymal stem cells resulted in a variety of clinical tolerance trials. Every approach has yielded promising results. However, the riddle of transplant tolerance has not been solved as of yet. The results of the on [...]

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