OBM Transplantation

(ISSN 2577-5820)

OBM Transplantation is an international peer-reviewed Open Access journal, which covers all evidence-based scientific studies related to transplantation, including: transplantation procedures and the maintenance of transplanted tissues or organs; assimilation of grafted tissue and the reconstitution of removed organs or parts of organs; transplantation of heart, lung, kidney, liver, pancreatic islets and bone marrow, etc. Areas related to clinical and experimental transplantation are also of interest.

OBM Transplantation is committed to rapid review and publication, and we aim at serving the international transplant community with high accessibility as well as relevant and high quality content.

We welcome original clinical studies as well as basic science, reviews, short reports/rapid communications, case reports, opinions, technical notes, book reviews as well as letters to the editor. 

Free Publication in 2019
Current Issue: 2019  Archive: 2018 2017

Special Issue

Current Advancement of Islet Cell Transplantation in the Treatment of Diabetes Mellitus

Submission Deadline: September 30, 2018 (Open)               Submit Now

Guest Editor

Kenneth L. Brayman, MD, PhD, FACS
Professor of Surgery, Medicine, and Biomedical Engineering, Director of Kidney, Pancreas and Islet Transplant Programs, Director of Center for Cellular Therapy and Biologic Theraputics. Department of Surgery, University of Virginia Health System, 1215 Lee Street, Charlottesville, VA 22908, USA
E-Mail: [email protected]
Website: https://surgery.virginia.edu/transplant/cfprofile/kenneth-brayman/
Research Interests: transplant immunosuppression, chronic allograft nephropathy, solid organ transplantation in patients with HIV, islet cell transplantation, transplantation tolerance, gene therapy and xenotransplantation

About This Topic

OBM Transplantation is an international peer-reviewed Open Access journal, which covers all evidence-based scientific studies related to transplantation. This is seeking original manuscripts for a Special Issue on cell-based therapy for diabetes: “Current Advancement of Islet Cell Transplantation in the Treatment of Diabetes mellitus” scheduled to appear in the first half of 2018.

Islet transplantation and pancreas transplantation have been becoming promising therapies for diabetes, which can restore normal blood glucose and prevent diabetes complications. However, there are many grand challenges for maintaining long-term graft function and insulin independence in diabetes patients.

The special issue will provide a forum for presenting current research works and clinical results showing advancement of cell-based therapy for diabetes, including auto-transplantation, all-transplantation, inflammatory reaction involved islet transplantation, islet macro and microencapsulation, stem cell therapy, as well as in vitro and in vivo imaging of the islets. The special issue will also be open to any author, but mainly invited by guest editor. Each submission will be reviewed by at least two reviewers to ensure a very high quality of papers selected for the Special Issue.

Publication

Open Access Review

Islet Identity in Transplantation Procedures: The Intersection of Cellular Maturity and Function

Christine A. Beamish, Omaima M. Sabek
Received: November 08, 2018; Published: March 05, 2019; doi:10.21926/obm.transplant.1901055

Open Access Review

Advances in Human Islet Processing: Manufacturing Steps to Achieve Predictable Islet Outcomes from Research Pancreases

David W. Scharp, Jayagowri Arulmoli, Kelly Morgan, Hannah Sunshine, Ergeng Hao
Received: October 15, 2018; Published: February 26, 2019; doi:10.21926/obm.transplant.1901052

Open Access Review

Targeting Acute Islet Inflammation to Preserve Graft Mass and Long-Term Function

Carly M. Darden, Srividya Vasu, Kenjiro Kumano, Bashoo Naziruddin, Michael C. Lawrence
Received: November 21, 2018; Published: January 29, 2019; doi:10.21926/obm.transplant.1901043

Open Access Review

Where’s Waldo? Extrahepatic Site Options for Islet Transplantation

Alexandria J Coughlan, Kendall R. McEachron, Mariya E. Skube, Sydne Muratore, Melena D. Bellin, Greg J Beilman
Received: October 29, 2018; Published: January 24, 2019; doi:10.21926/obm.transplant.1901042

Open Access Review

Chemical Strategies for Improving Islet Transplant Outcomes

Jeremy M. Quintana, Alexandra L. Stinchcomb, Jessica H. Kostyo, Blair M. Robichaud, Michael A. Plunk, Robert R. Kane
Received: October 8, 2018; Published: December 28, 2018; doi:10.21926/obm.transplant.1804036

Open Access Review

Application of Microfluidic Biochips for Human Islet Transplantation

Julianna Holzer, John Wu, Yi He, Mingyang Ma, Yuan Xing, Jose Oberholzer, Yong Wang
Received: November 08, 2018; Published: December 21, 2018; doi:10.21926/obm.transplant.1804034

Open Access Review

Evolution of Enzyme Requirements for Human Islet Isolation

Robert C. McCarthy, Michael L. Green, Francis E. Dwulet
Received: September 24, 2018; Published: November 8, 2018; doi:10.21926/obm.transplant.1804024

Open Access Original Research

Role of Automated Insulin Delivery (Artificial Pancreas) in Islet Transplantation: An In Silico Assessment

Dayu Lv, Jose Garcia-Tirado, Chiara Fabris
Received: May 17, 2018; Published: September 13, 2018; doi:10.21926/obm.transplant.1803019

Open Access Communication

Intrapancreatic Parenchymal Cell Transplantation as a Possible Model for the Development of a Cell-based Therapy for Type I Diabetes Mellitus

Masahiro Sato, Emi Inada, Shingo Nakamura, Issei Saitoh
Received: March 28, 2018; Published: August 4, 2018; doi:10.21926/obm.transplant.1803016

Open Access Case Report

Autoimmunity in Autologous Islet Transplantation

Khawla F. Ali, Vicente T. San Martin, Tyler Stevens, R. Matthew Walsh, Rita Bottino, Massimo Trucco, Betul Hatipoglu
Received: March 29, 2018; Published: July 3, 2018; doi:10.21926/obm.transplant.1803014

Open Access Review

Regulation of Inflammatory Response in Islet Transplantation

Yoshitaro Shindo, Mazhar A. Kanak
Received: March 29, 2018; Published: June 25, 2018; doi:10.21926/obm.transplant.1802013

Open Access Case Report

Delayed Clinically Significant Portal Hypertension after Total Pancreatectomy-Islet Auto-Transplantation

Nicholas Lim, Gregory Beilman, Timothy Pruett
Received: March 21, 2018; Published: June 12, 2018; doi:10.21926/obm.transplant.1802011

Open Access Review

Stem Cell Strategies to Promote Islet Transplantation Outcomes

Preeti Chhabra, Kenneth L. Brayman
Received: April 02, 2018; Published: June 5, 2018; doi:10.21926/obm.transplant.1802010

Open Access Review

Islet Xenotransplantation for the Treatment of Type 1 Diabetes

Masayuki Shimoda, Shinichi Matsumoto
Received: February 25, 2018; Published: April 25, 2018; doi:10.21926/obm.transplant.1802008

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