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Special Issue

Tumors of the Central Nervous System

Submission Deadline: October 15th, 2018 (Open)               Submit Now

Guest Editor

Antonio Meola M.D. Ph.D
Clinical Instructor in Neurosurgery, Department of Neurosurgery, Stanford University School of Medicine, 300 Pasteur Drive, Edwards Bldg. 94304, Stanford, CA
E-Mail: [email protected]
Research Interests: Brain Tumors, Skull Base Surgery, Image-guided Neurosurgery, Radiosurgery

About This Topic

The WHO classification of Tumors of the Central Nervous System (CNS) highlighted the pivotal role of molecular and genetic markers for predicting tumor biological behavior, therapy response and patient prognosis. We seek original research articles focusing on genetic, molecular and radiological features of CNS tumors that might impact on clinical practice, including clinical and preclinical data. Additionally, we invite submission of reviews, editorials, case reports, technical reports elucidating biological features of the CNS tumors, the interaction of tumors with healthy nervous tissue, as well as illustrating the effect of medications and cutting-edge technology on CNS tumor diagnosis and treatment.

Planned Papers

Title: Current Clinical Challenges in High Grade Meningioma
Authors: Blair Murphy, Jerry Jaboin
Affiliation: Knight Cancer Center, Oregon Health & Science University, Portland, Oregon, USA

Title: Effect of Tumoral Edema on Corticospinal Tractography: Changes After Surgical Removal
Authors: Ros de San Pedro. J, Cuartero Pérez. B
Affiliation: Regional Service of Neurosurgery, Hospital Clínico Universitario Virgen de la Arrixaca, El Palmar (Murcia), Spain.

Title: Diffuse Intrinsic Pontine Gliomas: Translation of Genomic Knowledge to Clinical Practice
Authors: Tina Zhou1, Sara Khan1,2,3,4, Ron Firestein1,2, Peter Downie3,4, Jason E Cain1,2
Affiliations: 1. Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, Victoria, Australia, 3168
2. Department of Molecular and Translational Medicine, School of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia, 3168
3. Monash Children’s Cancer Centre, Monash Children’s Hospital, Monash Health, Clayton, Victoria, Australia, 3168
4. Department of Paediatrics, Monash University, Clayton, Victoria, Australia, 3168

Title: Sporadic and hereditary hemangioblastoma: the role of endothelial cells
Authors: Alberto Feletti 1, Elena Bianchini 2, Anna De Gaetano 3, Lara Gibellini 2, Sara De Biasi 3, Giacomo Pavesi 1, Milena Nasi 2, Andrea Cossarizza 4, Marcello Pinti 3
1. Department of Neurosciences, Neurosurgery Unit, Azienda Ospedaliero-Universitaria di Modena, Modena, Italy
2. Department of Surgery, Medicine, Dentistry and Morphological Sciences, University of Modena and Reggio Emilia, Modena, Italy
3. Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy
4. Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Modena, Italy

Title: Magnetic resonance imaging approaches for predicting the response to hyperoxic radiotherapy in glioma-bearing rats
Authors: Nuria Arias-Ramos 1, Jesus Pacheco-Torres 1, 2, Pilar López-Larrubia 1, *
1. Instituto de Investigaciones Biomédicas "Alberto Sols", CSIC-UAM, Madrid, Spain
2. Division of Cancer Imaging Research, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA

Title: Indications for instrumented fusion during resection of intradural spinal cord tumors
Author: Michael Galgano
Department of Neurosurgery, SUNY Upstate Medical University, Syracuse, New York, United States

Title: Angiocentric Glioma: A Review of Clinicopathologic Features
Authors: Richard A. Prayson
Affiliation: Department of Anatomic Pathology, Cleveland Clinic, United States

Title: Sphingosine-1-phosphate in glioblastomamultiforme: from basic science to the clinic
Author: Laura Riboni
Affiliation: Department of Medical Biotechnology and Translational Medicine, LITA-Segrate, University of Milan, Milan, Italy

Title: Breaking the barrier – towards winning the race to enhance glioblastoma immunotherapy
Authors: Ignacio Mastandrea 1, Liat Rousso-Noori 1 and Dinorah Friedmann-Morvinski 1, 2
1. Department of Biochemistry and Molecular Biology, The George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel
2. Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel


Research Article

Magnetic Resonance Imaging Approaches for Predicting the Response to Hyperoxic Radiotherapy in Glioma-Bearing Rats

Nuria Arias-Ramos, Jesús Pacheco-Torres, Pilar López-Larrubia
Received: November 11, 2018; Published: January 31, 2019;  doi:10.21926/obm.neurobiol.1901020

Research Article

Correlation of CT and MR Perfusion and Permeability Parameters for Intracranial Tumors

Kirsten Greenlaw, Jai Jai Shiva Shankar
Received: October 7, 2018; Published: January 14, 2019;  doi:10.21926/obm.neurobiol.1901019

Case Report

Cerebellopontine Angle Glioblastoma with Concurrent Spinal Cord Involvement: A Case Report and Review of Literature

Rahul Abhyankar, Divya Mella, Edward Pan
Received: November 12, 2018; Published: January 4, 2019;  doi:10.21926/obm.neurobiol.1901018


Sleep Disorders in Children with Central Nervous System Tumors

Melissa A. Maloney, Katherine E. Lewinter, Sally L. Davidson Ward, Iris A. Perez
Received: November 13, 2018; Published: December 17, 2018;  doi:10.21926/obm.neurobiol.1804017

Original Research

TTF-1-Expressing Supratentorial Embryonal Tumors (PNET): A Clinicopathologic Study of Two Cases and Literature Review of TTF-1-Positive Primary Brain Tumors

Michele Bisceglia, Stefano Pizzolitto, Tullio Parracino, Giovanna De Maglio, Elena Minenna, Serena D’Agostini, Carlos A. Galliani
Received: October 7, 2018; Published: November 14, 2018;  doi:10.21926/obm.neurobiol.1804016


Angiocentric Glioma: A Review of Clinicopathologic Features

Richard A. Prayson, MD, MEd
Received: September 4, 2018; Published: November 5, 2018; doi:10.21926/obm.neurobiol.1804015

Case Report

A Case Series of Temozolomide in the Management of Refractory Prolactinomas

Divya B. Mella, Josie Sewell, Edward Pan
Received: October 12, 2018; Published: October 31, 2018; doi:10.21926/obm.neurobiol.1804014

Research Article

Isolated Diffusion Restriction Preceding Contrast Enhancement in Glioblastoma Multiforme is Associated with Short-Term Survival

Jai Jai Shiva Shankar, Adil Bata, Namita Sinha
Received: August 7, 2018; Published: October 26, 2018; doi:10.21926/obm.neurobiol.1804013


Craniopharyngiomas: An Appropriate Surgical Treatment based on Topographical and Pathological Concepts

Ruth Prieto, José M Pascual
Received: September 11, 2018; Published: October 16, 2018; doi:10.21926/obm.neurobiol.1804012


Contribution of PET Imaging to Clinical Management of Gliomas

Wolf-Dieter Heiss
Received: July 2, 2018; Published: September 20, 2018; doi:10.21926/obm.neurobiol.1803011