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Editor-in-Chief of OBM Hepatology and Gastroenterology

Osamu Yokosuka is an Emeritus Professor of Chiba University, Japan. He graduated from Chiba University School of Medicine in 1975 then worked as a trainee under Professor K. Okuda in Chiba University Hospital till 1978. Dr. Yokosuka was a research fellow worked under Professor S. Scherlock and Professor B. H. Billing in Royal Free Hospital, London, UK from 1978 to 1980; under Professor M. Omata in Chiba University from 1980 to 1985; and under Dr. J Summers in Fox Chase Cancer Center, PA, USA in 1984. In 1985, he received a Degree of Doctor of Medical Science, and served as an Assistant Professor in Chiba University till 1994, then as Lecturer in Medicine till 2006 when he was appointed as Director and Professor of Medicine. From 2013 to 2015, he served as the Dean of Chiba University School of Medicine.

Dr. Yokosuka was the Secretary General of APASL (2008-2014). In 2016, he was elected as the President of APASL Tokyo, the President of 52nd Annual Meeting of Japan Society of Hepatology, and the President of Funabashi Central Hospital. Dr. Yokosuka’s research mainly focuses on Hepatitis and Hepatocellular Carcinoma. So far, he has published more than 700 original papers.


The Associate Editor of OBM Hepatology and Gastroenterology

Tatsuo Kanda received a medical degree in 1991 at Niigata University School of Medicine, Japan, and his PhD in 1999 at Chiba University Graduate School of Medicine, Japan. He had post-doctor training for 3 years under Prof. Ratna Ray and Prof. Ranjit Ray at Saint Louis University, St. Louis, MO, USA. In Dec. 2008, Tatsuo Kanda became a Tenure-track Associate Professor at Department of Medicine and Clinical Oncology, Chiba University, Graduate School of Medicine, Japan. In Feb. 2013, Tatsuo Kanda was nominated a permanent Associate Professor at Department of Gastroenterology and Nephrology, Chiba University, Graduate School of Medicine, Japan. In 2017, Tatsuo Kanda became an Associate Professor, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Nihon University School of Medicine. For ~25 years, he has focused his scientific interests on the topics related to liver diseases including acute liver failure, viral hepatitis and autoimmune liver diseases, and worked with Prof. Osamu Yokosuka. Tatsuo Kanda is also an expert for hepatitis A virus (HAV), HBV and HCV, and translation and replication of these viruses, and hepatocarcinogenesis. With his expertise in antiviral therapies and hepatitis virus research, Tatsuo Kanda also sees a lot of patients in clinical daily practice. Tatsuo Kanda has published more than 200 articles in peer-reviewed Journal.

Special Issue

Genetic Screening

Submission Deadline: July 31, 2017 (Open)               Submit Now

Guest Editors

Joanne Traeger-Synodinos, DPhil (Oxon)
Associate Professor of Genetics, Department of Medical Genetics, School of Medicine, National and Kapodistrian University of Athens, Athens 11527, Greece
E-Mail: [email protected]
Research Interests: medical genetics; molecular genetics; reproductive genetics

François Rousseau, MD, MSc, FRCPC, FCAHS
Full Professor, Department of Medical Biology, Biochemistry and Pathology, Faculty of Medicine, Laval University, Québec, Québec G1L 3L5, Canada
E-Mail: [email protected]
Research Interests: laboratory medicine; evaluative research; population genetics; genetic epidemiology; technology transfer; health systems research

About This Topic

The impact of genetic diseases on health care systems, and society overall, is substantial. Diseases with a genetic component account for an significant proportion of death, morbidity, physical and/or mental handicap and disability, as well as reproductive failure (infertility, miscarriage etc). It is estimated that almost 8% of individuals up to the age of 25 years may be diagnosed with a genetic condition, over 30% of childhood hospital admissions have a disorder that is, at least partly, genetically determined, and the genetic component of many common multifactorial diseases should not be underestimated. 

Genetic screening aims to reduce the prevalence of genetic disorders and/or support decisions and choices with family planning by testing individuals without symptoms nor a family history of a genetic disease. Genetic screening thus involves the systematic and timely detection or exclusion of a hereditary disease, or the predisposition to a genetic disease or to establish if a person or couple carries a condition that could lead to a hereditary disease in offspring.

In this special issue of OBM Genetics, we have selected topics that highlight the progress, the state-of–the-art and future potential of genetic screening, ranging from practical and technological aspects through to social and ethical issues. Overall this issue provides information to promote and support optimal quality in standards of genetic screening in medical practice. 

Planned Papers

Title: Introduction on genetic screening
Authors: Joanne Traeger-Synodinos 1, François Rousseau 2
Affiliations: 1. Department of Medical Genetics, School of Medicine, National and Kapodistrian University of Athens, Athens 11527, Greece
2. Department of Medical Biology, Biochemistry and Pathology, Faculty of Medicine, Laval University, Québec, Québec G1L 3L5, Canada

Title: Neonatal screening programs for genetic diseases: current and future applications
Author: Yves Giguère
Affiliation: Programme québécois de Dépistage Néonatal Sanguin, CHU de Québec-Université Laval, Québec City, Québec, Canada

Title: Ethical and social issues related to Genetic Screening
Authors: Vardit Ravitsky 1, Bartha Knoppers 2
Affiliations: 1. Department of Human Genetics, Faculty of Medicine, McGill University, Canada
2. Department of social and preventive medicine, Université de Montréal, Canada



Responsible Implementation of Expanded Screening Programs for Genetic Diseases at the Beginning of Life

Martina C Cornel
Received: July 13, 2017; Published: February 12, 2018; doi:10.21926/obm.genet.1801013


Carrier Screening for Cystic Fibrosis: Past, Present and Future

Myrto Poulou, Maria Tzetis
Received: July 31, 2017; Published: November 3, 2017; doi:10.21926/obm.genet.1704010


Preimplantation Genetic Screening

Karen Sermon
Received: August 11, 2017; Published: October 27, 2017; doi:10.21926/obm.genet.1704009


Prenatal Screening for Fetal Aneuploidy

Sylvie Langlois, R Douglas Wilson
Received: Received: August 1, 2017; Published: September 27, 2017; doi:10.21926/obm.genet.1703007


Avoiding the Technological Imperative: Criteria for Genetic Screening Programs

Anne-Marie Laberge, Wylie Burke
Received: July 30, 2017; Published: September 25, 2017; doi:10.21926/obm.genet.1703006


Carrier Screening for the Haemoglobinopathies: Past, Present and Future

John Old, Cornelis Harteveld
Received: July 3, 2017; Published: August 15, 2017; doi:10.21926/obm.genet.1703005