OBM Transplantation is an international peer-reviewed Open Access journal, which covers all evidence-based scientific studies related to transplantation, including: transplantation procedures and the maintenance of transplanted tissues or organs; assimilation of grafted tissue and the reconstitution of removed organs or parts of organs; transplantation of heart, lung, kidney, liver, pancreatic islets and bone marrow, etc. Areas related to clinical and experimental transplantation are also of interest.
OBM Transplantation is committed to rapid review and publication, and we aim at serving the international transplant community with high accessibility as well as relevant and high quality content.
We welcome original clinical studies as well as basic science, reviews, short reports/rapid communications, case reports, opinions, technical notes, book reviews as well as letters to the editor.
Archiving: full-text archived in CLOCKSS.
Rapid publication: manuscripts are undertaken in 8 days from acceptance to publication (median values for papers published in this journal in 2021, 1-2 days of FREE language polishing time is also included in this period).
Lung and Heart Transplantation
Submission Deadline: November 15, 2020 (Open) Submit Now
David J. Ross, MD
Medical / Scientific Consultant, LLC, USA; Medical Director, Transplant Molecular Diagnostics, CareDX, Inc. USA
Research Interests: Lung transplantation; lung and heart transplantation; adult lung transplantation
About this topic
The field of cardiothoracic transplantation has experienced recent challenges mounting during the SARS-2 (CoVid-19) pandemic; nevertheless transplant volumes have since rebounded with a renewed sense of optimism and dedication. These experiences have highlighted the need for innovation with respect to modes of allograft surveillance, immunomodulation, and therapeutic strategies. Indeed, chronic allograft rejection remains an Achilles heel after solid organ transplantation which afflicts more than 50% of patients with chronic lung allograft dysfunction (CLAD) by 5-years after lung transplant, and cardiac allograft vasculopathy (CAV) by 10-years after heart transplantation .
Novel modes of pre-transplant mechanical circulatory device “bridging to transplantation” have experienced a renaissance, while protocols to expand donor organ availability for procurement have emerged, further enhancing post-transplant clinical outcomes.
In this special edition of OBM Transplantation, we invite authors for submission of articles which exemplify the spirit of innovation and creativity in this burgeoning cardiothoracic transplant field.
Chambers DC, Cherikh WS, Harhay MO, Hayes D, Hsich E, Khush KK, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult lung and heart–lung transplantation Report—2019; Focus theme: Donor and recipient size match. J Heart Lung Transplant. 2019; 38: 1042-1055.[CrossRef]
by Shehab Mohamed , Davide Tosi , Sara Pieropan , Andrea Cara , Giovanni Caffarena , Giorgio Alberto Croci and Lorenzo Rosso
Received: 01 July 2020; Published: 21 December 2020; doi: 10.21926/obm.transplant.2004129
Pulmonary transplantation (LuTx) is established as a treatment option for patients with end-stage lung diseases, such as chronic obstructive pulmonary disease, cystic fibrosis, interstitial lung disease, and pulmonary arterial hypertension. Acute rejection and infection are implicated as potential risk factors in developing complic [...]
Single-Center Outcomes of Heart Transplantation in Patients with Pulmonary Hypertension Bridged with Mechanical Circulatory Support
by Dominic Emerson , Jon Kobashigawa , Ryan Levine , Jamie Moriguchi , Dominick Megna , Joshua Chung , Dany Ramzy , Alfredo Trento and Fardad Esmailian
Received: 14 April 2020; Published: 06 July 2020; doi: 10.21926/obm.transplant.2003114
In advanced heart failure, orthotopic heart transplantation (OHT) remains the standard for definitive treatment. Patients with heart failure and concomitant pulmonary hypertension (PH) represent a challenging subgroup, with poor outcomes following OHT. Recently, Mechanical Circulatory Support (MCS) devices have been utilized as a bridge to [...]
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