TY  - JOUR
AU  - Ruaengsri, Chawannuch
AU  - Alvarez-Cortes, Miguel
AU  - Leon, Marc
AU  - Quiroz-Flores, Manuel
AU  - Shibata, Masafumi
AU  - Shudo, Yasuhiro
PY  - 2025
DA  - 2025/12/30
TI  - Optimizing Donor Management Strategies for DCD Lung Procurement
JO  - OBM Transplantation
SP  - 261
VL  - 09
IS  - 04
AB  - Donation after circulatory death (DCD) offers a vital strategy to expand the donor lung pool; however, DCD lungs are uniquely susceptible to warm ischemic injury during procurement. This chapter reviews evidence-based and emerging donor management strategies aimed at mitigating ischemic damage and optimizing the suitability of DCD lungs for transplantation, encompassing hemodynamic and ventilatory optimization, bronchoscopic clearance, targeted pharmacological interventions, and strategies to minimize transfusion requirements. Remote monitoring holds promise for further improving lung quality. Optimizing donor management strategies is critical to maximizing the utilization of DCD lungs, and future research should focus on refining existing protocols, evaluating new technologies, and addressing ethical considerations to ensure equitable access to lung transplant.
SN  - 2577-5820
UR  - https://doi.org/10.21926/obm.transplant.2504261
DO  - 10.21926/obm.transplant.2504261
ID  - Ruaengsri2025
ER  -