TY  - JOUR
AU  - Velasquez, Camilo A.
AU  - Yaguare, Simon
AU  - Gambini, Sabrina
AU  - McElhiney, Elizabeth
AU  - Keshavamurthy, Suresh
PY  - 2025
DA  - 2025/04/27
TI  - What Is the Current Status of Single Lung Transplantation? A Literature Review
JO  - OBM Transplantation
SP  - 248
VL  - 09
IS  - 02
AB  - Lung transplantation (LTx) is the gold standard for the surgical treatment of end-stage lung disease. Ongoing discussions persist whether single lung transplantation (SLT) or bilateral lung transplantation (BLT) lead to better patient outcomes and quality of life. This study analyzed 58 peer-reviewed articles from 1990 to 2024, comparing SLT and BLT across several parameters, including indications for transplantation, overall survival, pulmonary hypertension, complications, chronic rejection, functional status, and quality of life outcomes. The review also addressed native lung complications, the future of lung transplantation, and the outcomes of non-transplanted lungs in SLT cases. Bilateral lung transplantation (BLT) may offer a more definitive solution for bilateral lung disease. However, the choice between single lung transplantation (SLT) and BLT should be personalized according to each patient's unique requirements. Further research is needed to elucidate each approach's specific advantages and limitations, enhance patient outcomes, and refine lung transplantation practices.
SN  - 2577-5820
UR  - https://doi.org/10.21926/obm.transplant.2502248
DO  - 10.21926/obm.transplant.2502248
ID  - Velasquez2025
ER  -