TY  - JOUR
AU  - Pham, Christine
AU  - Pierce, Brett J
AU  - Yau, Simon W
AU  - Youssef, Jihad Georges
AU  - Goodarzi, Ahmad
AU  - Huang, Howard J
PY  - 2021
DA  - 2021/08/30
TI  - Belatacept Dosing in Lung Transplantation: Is There a Method to the Madness?
JO  - OBM Transplantation
SP  - 152
VL  - 05
IS  - 03
AB  - Data supporting the use of belatacept in non-abdominal organs are limited to case series and small cohorts involving patients requiring conversion due to CNI intolerance or contraindication. Review articles summarizing the efficacy of belatacept salvage therapy in lung transplantation have previously been published, however, dosing regimens are highly variable and uniform guidance is lacking. In this article, indications and considerations for belatacept use in lung transplant recipients are reviewed with a specific focus on dosing regimens. Utilization of standardized dosing protocols to guide belatacept conversion will both improve the ability to directly assess outcomes and provide the opportunity to improve future patient care. A suggested framework for dosing selection and timeline for cross titration is proposed herein.
SN  - 2577-5820
UR  - https://doi.org/10.21926/obm.transplant.2103152
DO  - 10.21926/obm.transplant.2103152
ID  - Pham2021
ER  -