TY  - JOUR
AU  - Chaba, Anis
AU  - Oniszczuk, Julie
AU  - Dekeyser, Manon
AU  - Durrbach, Antoine
PY  - 2021
DA  - 2021/01/11
TI  - The Puzzle of Immunosuppressive Drugs
JO  - OBM Transplantation
SP  - 133
VL  - 05
IS  - 01
AB  - Kidney transplantation has become the preferred treatment option in end-stage chronic renal failure as it provides significant improvements over dialysis in terms of both quality and duration of life. Even after several randomized studies conducted in the last 20 years, the combination of CNI, MMF, and steroids continues to be considered the gold standard for kidney transplantation. However, novel molecules aimed at minimizing renal and cardiovascular toxicity, particularly with CNI sparing, are being identified. The present review assesses various such molecules available currently and briefly discusses the existing combination strategies and novel perspectives for the redesigning of protocols based on our novel therapeutic arsenal.
SN  - 2577-5820
UR  - https://doi.org/10.21926/obm.transplant.2101133
DO  - 10.21926/obm.transplant.2101133
ID  - Chaba2021
ER  -