TY  - JOUR
AU  - Ferrarese, Alberto
AU  - Senzolo, Marco
AU  - Burra, Patrizia
PY  - 2020
DA  - 2020/05/18
TI  - Multidrug-Resistant Bacterial Infections before and after Liver Transplantation
JO  - OBM Transplantation
SP  - 110
VL  - 04
IS  - 02
AB  - Bacterial infection represents a common event in the natural history of cirrhosis, especially in patients with end-stage liver disease. An episode of bacterial infection may significantly modify a patient’s outcome in the setting of liver transplantation (LT) by impairing hepatic and extrahepatic organ functions, both in pre-operative and post-operative phases. Infections caused by multidrug-resistant organisms (MDRO) are increasing in cirrhosis due to high antibiotic exposure and hospitalizations. This issue is particularly important in the LT setting, where MDRO infections occurring before surgery and during the early days after surgery might significantly impair graft function and patient outcome. This review summarizes the recently published findings on the occurrence of MDRO infection before and after LT, and new perspectives for its prevention and treatment.
SN  - 2577-5820
UR  - https://doi.org/10.21926/obm.transplant.2002110
DO  - 10.21926/obm.transplant.2002110
ID  - Ferrarese2020
ER  -