TY - JOUR AU - Krishnan, Sheila AU - Hage, Chadi AU - Coakley, Raymond AU - van Duin, David AU - Lobo, Leonard Jason PY - 2019 DA - 2019/06/10 TI - Respiratory Viral Infections in Lung Transplant Recipients: Implications for Long Term Outcomes and Emerging Therapies JO - OBM Transplantation SP - 065 VL - 03 IS - 02 AB - Lung transplant recipients are at greater risk of respiratory viral infections as compared to other solid organ transplant recipients due to constant exposure of the allograft to the external environment. There are no standardized methods for surveillance, prevention, or treatment of these infections despite their association with increased morbidity and mortality. Various studies have linked respiratory viral infections with acute cellular rejection and chronic allograft dysfunction, and emerging data indicates a role in antibody mediated rejection. This paper will review the prevalence and impact of community acquired respiratory viruses in lung transplant recipients, review the evidence linking these viral infections to long term graft dysfunction and rejection, describe existing strategies for surveillance and prevention, and list the currently available, and promising investigational therapies. SN - 2577-5820 UR - https://doi.org/10.21926/obm.transplant.1902065 DO - 10.21926/obm.transplant.1902065 ID - Krishnan2019 ER -