TY  - JOUR
AU  - Oberholzer, Jose
AU  - Xing, Yuan
AU  - Holzer, Julianna
AU  - Wu, John
AU  - He, Yi
AU  - Ma, Mingyang
AU  - Wang, Yong
PY  - 2018
DA  - 2018/12/21
TI  - Application of Microfluidic Biochips for Human Islet Transplantation
JO  - OBM Transplantation
SP  - 034
VL  - 02
IS  - 04
AB  - In this review, we discuss the application of microfluidic devices in studying the physiology and pathophysiology of human islets and beta-cells, especially its application for human islet transplantation. Human islet transplantation is a promising therapy for Type I diabetes; however, the islet transplant outcomes for achieving complete insulin independence are far from perfect and face many challenges. This review focuses on the microfluidic devices developed in our laboratory, which can address these challenges in the field of human islet transplantation, and briefly review the design and fabrication principles of these microfluidic devices and their main application.
SN  - 2577-5820
UR  - https://doi.org/10.21926/obm.transplant.1804034
DO  - 10.21926/obm.transplant.1804034
ID  - Oberholzer2018
ER  -