TY - JOUR AU - Shichkin, Valentin P. AU - Kurchenko, Oleg V. PY - 2026 DA - 2026/07/13 TI - Review of Phytochemical Composition and Impact of <i>Potentilla alba</i> Extracts on Thyroid Health and Immunity JO - Recent Progress in Nutrition SP - 015 VL - 06 IS - 03 AB - Thyroid disorders are an actual global health concern requiring diverse therapeutic strategies. Potentilla alba (P. alba), commonly known as White cinquefoil, has been used in folk medicine for its rich composition of microelements and pharmacologically essential phytocompounds. It has now also gained recognition in evidence-based medicine for its potential to treat thyroid dysfunction, particularly hypothyroidism and nodular goiter. However, the complicated composition of P. alba extracts makes it difficult to predict the final results of such treatment and to understand its therapeutic mechanisms. The review aims to synthesize the current knowledge of the phytochemical composition of P. alba extracts and to analyze the mechanisms underlying its complex effects on thyroid health. Additionally, the analysis reviews the efficacy and side effects of P. alba extracts in preclinical and clinical research, highlighting key challenges and proposing approaches to address them. SN - 2771-9871 UR - https://doi.org/10.21926/rpn.2603015 DO - 10.21926/rpn.2603015 ID - Shichkin2026 ER -