TY  - JOUR
AU  - Briggs, Sam
AU  - Monroe, Mary Beth B
AU  - Weizbicki, Mark
AU  - Hasan, Sayyeda Marziya
AU  - Maitland, Duncan
PY  - 2021
DA  - 2021/06/25
TI  - Influence of Aging, Sterilization, and Composition on the Degradation of Polyurethane Foams
JO  - Recent Progress in Materials
SP  - 025
VL  - 03
IS  - 02
AB  - Shape memory polymers (SMPs) are highly attractive materials for medical devices. Specifically, SMP foams are currently being used as embolic devices in peripheral and cerebral vascular applications. To ensure the proper function and safety of these materials in their intended applications, it is important to understand how processing treatments, such as aging, sterilization, and foam composition can influence their degradation. Here, SMP foams were treated with industry relevant processing parameters, and the influence on degradation was observed via gravimetric, chemical, and morphological studies. Accelerated thermal aging was shown to have an influence on material degradation rate in real time oxidative studies. Sterilization was performed via Electron beam (E-beam) irradiation at the high and low dosages commonly used in industry and had no significant influence on foam degradation profiles. These findings help inform appropriate treatment of SMP foam embolic devices to ensure their safety and efficacy.
SN  - 2689-5846
UR  - https://doi.org/10.21926/rpm.2102025
DO  - 10.21926/rpm.2102025
ID  - Briggs2021
ER  -