TY - JOUR AU - Norris, Emma AU - Dalecki, Diane AU - Hocking, Denise PY - 2020 DA - 2020/07/21 TI - Using Acoustic Fields to Fabricate ECM-Based Biomaterials for Regenerative Medicine Applications JO - Recent Progress in Materials SP - 018 VL - 02 IS - 03 AB - Ultrasound is emerging as a promising tool for both characterizing and fabricating engineered biomaterials. Ultrasound-based technologies offer a diverse toolbox with outstanding capacity for optimization and customization within a variety of therapeutic contexts, including improved extracellular matrix-based materials for regenerative medicine applications. Non-invasive ultrasound fabrication tools include the use of thermal and mechanical effects of acoustic waves to modify the structure and function of extracellular matrix scaffolds both directly, and indirectly via biochemical and cellular mediators. Materials derived from components of native extracellular matrix are an essential component of engineered biomaterials designed to stimulate cell and tissue functions and repair or replace injured tissues. Thus, continued investigations into biological and acoustic mechanisms by which ultrasound can be used to manipulate extracellular matrix components within three-dimensional hydrogels hold much potential to enable the production of improved biomaterials for clinical and research applications. SN - 2689-5846 UR - https://doi.org/10.21926/rpm.2003018 DO - 10.21926/rpm.2003018 ID - Norris2020 ER -