TY  - JOUR
AU  - Jason, Leonard A.
AU  - Kalns, John
AU  - Ruesink, Lauren
AU  - Katz, Ben Z.
PY  - 2026
DA  - 2026/10/25
TI  - Saliva Fatigue Biomarker Index in a COVID Sample
JO  - OBM Neurobiology
SP  - 358
VL  - 10
IS  - 04
AB  - Following COVID, some individuals have developed Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). We assessed whether a salivary biomarker of fatigue could identify young adults with ME/CFS following COVID. We examined the ratio of the concentrations of 2 peptide fragments in saliva, referred to as the Fatigue Biomarker Index (FBI), in participants from our study diagnosed with severe ME/CFS, moderate ME/CFS, and recovered controls. Participants classified with severe ME/CFS exhibited higher FBI values than participants with moderate ME/CFS and recovered controls. These findings are exploratory and require replication in larger, adequately powered studies.
SN  - 2573-4407
UR  - https://doi.org/10.21926/obm.neurobiol.2604358
DO  - 10.21926/obm.neurobiol.2604358
ID  - Jason2026
ER  -