TY  - JOUR
AU  - Qamar, Mehwish
AU  - Ahmad, Asma Hayati
AU  - Sulong, Sarina
AU  - Tauseef, Ambreen
AU  - Azman, Khairunnuur Fairuz
PY  - 2026
DA  - 2026/05/05
TI  - Neurotransmitters in the Modulation of Stress: A Bibliometric Mapping and Visual Analysis (2000–2023)
JO  - OBM Neurobiology
SP  - 334
VL  - 10
IS  - 02
AB  - Stress is a multifaceted response involving physiological, psychological, and behavioural processes, with neurotransmitters such as serotonin, dopamine, and norepinephrine playing key modulatory roles. This study aimed to map global research trends on stress and neurotransmitters, identify thematic clusters, and highlight emerging frontiers relevant to health and disease. A bibliometric analysis was conducted on 4,132 publications indexed in Scopus between 2000 and 2023. Data were retrieved and processed using Excel and Harzing’s Publish or Perish, and analyzed with VOSviewer to generate co-authorship, co-occurrence, and citation network visualizations. Publications on stress and neurotransmitters have shown a consistent upward trend over the past two decades. The United States, China, and Japan emerged as the leading contributors. Core keywords included stress, neurotransmitters, serotonin, dopamine, glutamate, depression, anxiety, and oxidative stress. Emerging terms such as antioxidants, neuroprotection, inflammation, BDNF, GABA, acetylcholinesterase, metabolism, and gene expression indicate growing interest in neurochemical pathways and their role in mental and neurodegenerative disorders. The network analysis revealed strong global collaboration and multidisciplinary research across neuroscience, psychology, and molecular biology. This study provides the first comprehensive bibliometric mapping of global research on the links between stress and neurotransmitters. By highlighting established themes and emerging areas such as BDNF-related signaling and metabolic-neurochemical interactions, the findings contribute to a deeper understanding of stress modulation mechanisms. These insights may guide future translational research and inform the development of targeted strategies for managing stress-related physical and mental health disorders.
SN  - 2573-4407
UR  - https://doi.org/10.21926/obm.neurobiol.2602334
DO  - 10.21926/obm.neurobiol.2602334
ID  - Qamar2026
ER  -