TY - JOUR AU - Ismail, Samhani AU - Nashron, Muhammad Hakimi Mohd AU - Jusoh, Mohd Hanifah AU - Sadagatullah, Abdul Nawfar PY - 2025 DA - 2025/08/05 TI - Advancing Objective Pain Measurement: Exploring the Potential of Electroencephalography Biomarkers JO - OBM Neurobiology SP - 296 VL - 09 IS - 03 AB - Chronic pain involves complex cortical and subcortical changes, suggesting that brain electrical activity may be a potential biomarker for nociceptive processing. Pain leaves its signature in the brain's oscillatory patterns, yet limited studies have explored the neurophysiological alterations associated with chronic pain. This review examines the pain detection method currently used in clinical settings, the potential of neurophysiological features to become brain oscillatory brain biomarkers, and their use in future medical advances. SN - 2573-4407 UR - https://doi.org/10.21926/obm.neurobiol.2503296 DO - 10.21926/obm.neurobiol.2503296 ID - Ismail2025 ER -