TY  - JOUR
AU  - Danilov, Igor Val
AU  - Medne, Dace
AU  - Mihailova, Sandra
PY  - 2025
DA  - 2025/07/03
TI  - Natural Neurostimulation for Chronic Pain Management: A Case Series of 3 Patients with Dysmenorrhea and Menstrual Migraine
JO  - OBM Neurobiology
SP  - 290
VL  - 09
IS  - 03
AB  - Accumulating evidence suggests that chronic pain occurs in various disorders due to correlated processes of spontaneous cortical reorganization and dysregulation of cortical excitability in consciousness-related networks. This case series tracks three patients with chronic pain associated with the menstrual cycle treated by a novel non-invasive brain stimulation technique that applies qualities of the mother-fetus neurocognitive model. Previous research has shown that a low-frequency pulsed electromagnetic field and a complex acoustic wave from the mother’s heart contribute to the synchronization of these two nervous systems, thereby developing a balanced nervous system in fetuses. Therefore, we hypothesize that the scaled parameters of these natural forces can be used to treat an injured nervous system in adults. Acoustic photonic intellectual neurostimulation (APIN) emulates the central parameters of this natural brain stimulation during pregnancy. Based on evidence from previous research, we suppose that weak stimulations with these therapeutic agents excite different neuronal networks in specific consciousness-related brain areas; their integrated impact modulates mitochondrial functions and causes neuronal tissue oxygenation and adenosine-5’-triphosphate protein release, leading to pain relief and facilitating neuronal plasticity. This sequence of physicochemical interactions produces a change in brain connectivity that supports a change in symptoms such as chronic pain. The case series of three patients shows a therapeutic effect.
SN  - 2573-4407
UR  - https://doi.org/10.21926/obm.neurobiol.2503290
DO  - 10.21926/obm.neurobiol.2503290
ID  - Danilov2025
ER  -