TY  - JOUR
AU  - Jafari, Siavash
AU  - Vaughan, Mariko
AU  - Baharlou, Souzan
AU  - Ghadiri, Pooria
AU  - Hassanabadi, Nazila
AU  - Nasr, Ashkan
PY  - 2019
DA  - 2019/09/09
TI  - Impact of Case Management on HIV Patients’ Linkage to Care and Their Clinical Outcome: A Systematic Review of Randomized Clinical Trials
JO  - OBM Neurobiology
SP  - 039
VL  - 03
IS  - 03
AB  - Objectives: The purpose of this systematic literature review is to investigate the impact of case management on the link between HIV/AIDS patients (HIV-infected persons) and HIV treatment, and to investigate the impact of case management on their morbidity and mortality. 
Methods: We searched PubMed, Current Contents, Scopus, EMBASE, MEDLINE, the Effect Review Summary Database and the ACP Journal Club until May 2018. A randomized clinical trial examined the impact of case management on the association of PLHA with care and publications in English. After reviewing the title and abstract, the full text of the included study is retrieved for in-depth review. Two commentators reviewed the articles and extracted relevant information.
Results: Six randomized controlled trials were selected for inclusion in the systematic review. We found significant heterogeneity in the included studies. These studies use a wide range of definitions and provide a variety of services under case management services. One study found a statistically significant reduction in mortality and viral load reductions, but there was no difference in CD4 counts in the case management group. Two studies have found that case management patients are more closely linked to HIV care. Three studies found no difference in treatment initiation rates and treatment initiation time between the two groups. One study did not find an improvement in CD4 counts. One study reported an increase in viral load.
SN  - 2573-4407
UR  - https://doi.org/10.21926/obm.neurobiol.1903039
DO  - 10.21926/obm.neurobiol.1903039
ID  - Jafari2019
ER  -