TY - JOUR AU - Zhou, Tina AU - Khan, Sara AU - Firestein, Ron AU - Downie, Peter AU - Cain, Jason PY - 2019 DA - 2019/03/12 TI - Diffuse Intrinsic Pontine Glioma: Translation of Genomic Knowledge to Clinical Practice JO - OBM Neurobiology SP - 022 VL - 03 IS - 01 AB - Pediatric brain tumors account for approximately 25% of all cancers in children and are currently the leading cause of cancer-related deaths in the pediatric population with an estimated incidence of 5.14 cases per 100,000 persons [1]. Up to 10-15% of all pediatric brain tumors arise in the brainstem, with the majority of these classified as the diffuse intrinsic pontine glioma (DIPG) subtype [2]. The outcome of children with DIPG remains dismal with a median survival of SN - 2573-4407 UR - https://doi.org/10.21926/obm.neurobiol.1901022 DO - 10.21926/obm.neurobiol.1901022 ID - Zhou2019 ER -