TY  - JOUR
AU  - Prayson, Richard
PY  - 2018
DA  - 2018/11/05
TI  - Angiocentric Glioma: A Review of Clinicopathologic Features
JO  - OBM Neurobiology
SP  - 015
VL  - 02
IS  - 04
AB  - Along with focal cortical dysplasia, hippocampal sclerosis and remote infarcts, tumors are a well known cause of medically intractable or pharmacoresistent epilepsy [1-3].  Most of the tumors encountered in this setting represent low grade glioneuronal neoplasms, particularly gangliogliomas and dysembryoplastic neuroepithelial tumors.  In 2005, Wang and colleagues reported on 8 tumors which they designated as so-called “monomorphous angiocentric gliomas” [4].  The title of their paper suggested that these tumors were epileptogenic (all eight patients had epilepsy) and displayed features of infiltrating astrocytoma and ependymoma.  During the same month, Lellouch-Tubiana and coworkers reported on a series of 10 children with refractory epilepsy who had similar appearing neoplasms which they referred to as “angiocentric neuroepithelial tumors” [5]. The term “angiocentric glioma” was used in reference to these tumors in a series of eight tumors reported by Preusser et al in 2007 [6] and the entity was included under this designation in the 2007 World Health Organization (WHO) Classification of Tumours of the Central Nervous System [7].
	The purpose of this article is to briefly review the salient clinical and pathologic features of this relatively new entity
SN  - 2573-4407
UR  - https://doi.org/10.21926/obm.neurobiol.1804015
DO  - 10.21926/obm.neurobiol.1804015
ID  - Prayson2018
ER  -