TY - JOUR AU - de Almeida, Regiani Aparecida AU - Vicente de Paula Rezende, Ricardo AU - Reitz Cardoso, Flavia Aparecida AU - Cardozo Filho, Lucio PY - 2023 DA - 2023/04/18 TI - Non-Isothermal Compressible Flow Model for Analyzing the Effect of High CO<sub>2</sub> Inlet Flow Rate on Particle Size in a Supercritical Antisolvent Process JO - Journal of Energy and Power Technology SP - 016 VL - 05 IS - 02 AB - In this work with CFD simulations, the evaluation of the supercritical anti-solvent (SAS) process for producing nanoparticles from an expanded solution of ethanol/solute in carbon dioxide is reported. The influence of the solution and antisolvent flow rates on mean particle size, the flow dynamic, and the supercritical mixture's jet velocity must be well established in the literature and analyzed. The high flow rate of the anti-solvent resulted in increased mean particle sizes for all studied cases. At the lowest flow rate of CO2 examined, an increase in the solvent flow rate [0.3-1.0] ml/min initially led to a decrease of 11.2% in the mean particle diameter (MPD); however, further increasing the solvent flow rate [1.0-2.0]ml/min was an increase of 33% in this parameter. At the highest CO2 flow rate, the behavior of MPS was the opposite; it had a rise de 13.5% in MPD with an increase in solvent flow rate; further increasing the flow rate of the solvent, there was a drop of 8.6% in MPD. Significant variations in the temperature lead to large fluctuations in the particle diameters. At last, the contact zones between CO2 and ethanol were delimited, favoring the understanding of the influence of the flow patterns generated by the variation of the flow rates in the mean particle diameters. SN - 2690-1692 UR - https://doi.org/10.21926/jept.2302016 DO - 10.21926/jept.2302016 ID - de Almeida2023 ER -