TY  - JOUR
AU  - Vassão, Patricia Gabrielli
AU  - Laakso, E-Liisa
PY  - 2022
DA  - 2022/03/21
TI  - Photobiomodulation Therapy (PBMT) is Feasible and Acceptable in Pre-conditioning and Post-operative Recovery of Patients after Total Knee arthroplasty (TKA): A Clinical Case Series
JO  - OBM Integrative and Complementary Medicine
SP  - 012
VL  - 07
IS  - 01
AB  - Photobiomodulation therapy (PBMT) for minimal to moderate Kellgren and Lawrence grade knee osteoarthritis has significant evidence for effectiveness. The effect of PBMT in severe grades of osteoarthritis is less clear; and no studies have investigated the effect of PBMT before and after knee replacement surgery. This small study (n=4) aimed to understand the potential feasibility of undertaking a future randomised controlled clinical trial of a self-administered, home-based light patch system before and after total knee arthroplasty (TKA) The PBM device (450nm (6.75 mW/cm2) and 640nm (2.25 mW/cm2); 33kHz frequency, 4.5 J/cm2 radiant exposure) was self-applied by patients daily for 30 minutes for one week before, and 3 times in the week following hospital discharge after TKA. We measured numeric pain ratings, physical function and patient-reported outcomes at baseline one week prior to surgery, the day prior to surgery, at Day 4 after surgery, and at 1, 2, 4 and 6 weeks after hospital discharge. The study protocol and methods were found to be feasible and acceptable to participants. No pain was reported by any participants at 6-week follow-up. Functional measures of timed-up-and-go and 30 second chair stands test demonstrated marked improvement over the study period. No patients were requiring opioid analgesia at 6-week follow-up. Limitations included lack of gender diversity, the small number of participants and absence of information about post-hospital discharge opioid analgesic requirements from control group. The results provide confidence in progressing this research in an adequately powered, placebo-controlled, randomised clinical trial.
SN  - 2573-4393
UR  - https://doi.org/10.21926/obm.icm.2201012
DO  - 10.21926/obm.icm.2201012
ID  - Vassão2022
ER  -