TY - JOUR AU - James, Randolph AU - Moore, Amy AU - Carpenter, Dick AU - Miller, Terissa AU - Ledbetter, Christina PY - 2019 DA - 2019/09/06 TI - Feasibility of a Functional Medicine Approach to Slowing Clinical Cognitive Decline in Patients over Age 55: A Multiple Case Study Report JO - OBM Integrative and Complementary Medicine SP - 054 VL - 04 IS - 03 AB - (1) Background: The current study examined a multifaceted anti-neuroinflammatory intervention that included physical exercise, mental exercise, grain-free/sugar-free diet, anti-inflammatory nutritional supplements, sleep optimization, and stress management within the context of a functional medicine practice for five patients with varying levels of cognitive impairment. (2) Methods: In a prospective chart review, we examined impact measures including assessment of cognitive skills, brain connectivity, and daily functioning. (3) Results: Three of the five patients were no longer classified as cognitively impaired, while a fourth patient improved from moderately-to-severely impaired to mildly impaired. Patients reported improved memory, mental clarity, and outlook on life. fMRI analyses revealed changes in brain connectivity and efficiency. (4) Conclusions: The current study provides preliminary support for and feasibility of the use of a multi-component approach to slowing cognitive decline. SN - 2573-4393 UR - https://doi.org/10.21926/obm.icm.1903054 DO - 10.21926/obm.icm.1903054 ID - James2019 ER -