TY - JOUR AU - Berberich, Megan AU - Bernstein, Bettina PY - 2018 DA - 2018/11/13 TI - What is the Current Evidence to Support the Use of Herbs and Supplements to Treat Mood and Anxiety Disorders? JO - OBM Integrative and Complementary Medicine SP - 030 VL - 03 IS - 04 AB - Abstract: (1) Background: • Treatment of mood and anxiety disorders with supplements, herbs and nutraceuticals (dietary supplements) is at this point viewed as an integrative or alternative treatment, however these substances have been around for quite some time and are regarded as basic to the understanding of human biochemistry, physiology, health and illness in medicine. (2) Methods: • This review article was done using a literature search utilizing the National Library of Medicine online data base and the PCOM electronic library data base of 1,707,669 academic journals to include studies utilizing herbs and supplements for depression and anxiety published in the past 10 years. Studies of a positive and negative type were both included in this review article. (3) Results: • Step wise approach to depression and anxiety should first address insomnia. • Reduction of the risk of self-harm should be addressed and reduction of oxidative stress is desirable especially for young adults and adolescents. • Effect size differs between supplements. (4) Conclusions: • Side effect profile should be taken into consideration when choosing supplements or herbal preparations. • Gender may impact response to different herbs and supplements. • Future research trials are needed to confirm best practices. SN - 2573-4393 UR - https://doi.org/10.21926/obm.icm.1804030 DO - 10.21926/obm.icm.1804030 ID - Berberich2018 ER -