TY - JOUR AU - Picchi, Marco AU - Di Stefano, Mariella AU - Nurra, Linda AU - Rossi, Antonella AU - Ventura, Leonardo AU - Noberasco, Cristina AU - Rossi, Elio PY - 2018 DA - 2018/09/03 TI - Homeopathy and Complementary Integrative Medicine, Dietary and Lifestyle Advices to Reduce Adverse-Effects of Anti-Cancer Therapy: A Cohort Study with Breast Cancer Patients JO - OBM Integrative and Complementary Medicine SP - 017 VL - 03 IS - 03 AB - Background. To face adverse-effects of anti-cancer treatment, the Homeopathic Clinic of Lucca, in collaboration with the Oncology Department, has set up an Integrative Oncology Outpatient Unit in the Public Hospital Campo di Marte, Aim. To present the results of complementary medicine (CM) treatment targeted towards reducing the adverse effects of anti-cancer therapy and cancer symptoms and improving the quality of life of breast cancer patients. Methods. This is a retrospective observational study conducted on 204 breast cancer patients (all females except 1 male) were consecutively visited from September 2013 to December 2017, mean age 54.8 (35-88) years. Almost all patients were referred by their medical oncologists. The intensity of symptoms was evaluated according to a grading system from G0 (absence of symptoms) to G1 (slight), G2 (moderate), and G3 (strong), as evaluated by the patient in conjunction with the doctor during the course of the visits. The severity of radiodermatitis was evaluated with the Radiation Therapy Oncology Group (RTOG) scale. Homeopathy was the main prescribed therapy, either exclusive (47.5%) or integrated with other complementary medicines (41.7%), mainly botanicals and acupuncture. The Banerji protocol was applied in 3.4% of patients. Results. The most frequently treated symptoms were the adverse-effects of anti-cancer therapies (84.3%): endocrine therapy (36.3%), chemotherapy (33.3%), radiotherapy (9.8%) and surgery (4.9%). The symptoms caused by cancer disease were 25.5%, and comorbidity 21.6%. Comparison of the clinical conditions before and after treatment allowed to observe a significant amelioration of the following symptoms: hot flashes (p < 0.01); nausea (p < 0.01); fatigue (p < 0.01); anxiety (p < 0.05); depression (p < 0.01); insomnia (p < 0.01); mucositis (p < 0.01); joint pain (p < 0.01) . Conclusions. A clinic of integrative oncology is an opportunity to reduce adverse-effects of anti-cancer therapy and to ameliorate cancer patients’ quality of life. SN - 2573-4393 UR - https://doi.org/10.21926/obm.icm.1803017 DO - 10.21926/obm.icm.1803017 ID - Picchi2018 ER -