TY - JOUR AU - Baumann, Julia AU - Bönzli, Eva AU - Wandrey, Franziska AU - Grothe, Torsten PY - 2025 DA - 2025/04/03 TI - Moldavian Dragonhead Extract: A Natural Collagen-Booster to Target Skin Aging JO - OBM Geriatrics SP - 305 VL - 09 IS - 02 AB - The complex process of skin aging results in noticeable changes, including decreased collagen content, reduced elasticity, and decreased hydration. Interventions to preserve or restore collagen, a key structural protein, may help counteract these signs. The concept of "beauty from within” through nutritional supplements is of growing interest, particularly the use of plant-based alternatives to animal-derived or synthetic collagen. This study investigated the anti-aging potential of an extract from Moldavian dragonhead (Dracocephalum moldavica L.), a natural plant-based compound. In vitro studies have shown that the extract stimulates genes crucial for skin structure. Further, a double-masked, randomized, placebo-controlled clinical trial in female volunteers demonstrated that oral supplementation with the extract significantly improves skin hydration and increases dermal and full-skin thickness. These findings suggest that the Moldavian dragonhead extract is a promising natural alternative to traditional interventions, offering a holistic approach to improve the skin's dermal network and combat skin aging. SN - 2638-1311 UR - https://doi.org/10.21926/obm.geriatr.2502305 DO - 10.21926/obm.geriatr.2502305 ID - Baumann2025 ER -