TY  - JOUR
AU  - Durand, Florence
AU  - Bouaziz, Noomane
AU  - Braha-Zeitoun, Sonia
AU  - Isaac, Clémence
AU  - Schenin-King Andrian, Palmyre
AU  - Januel, Dominique
PY  - 2018
DA  - 2018/06/11
TI  - The Positive Effect of Long-Term Repetitive Transcranial Magnetic Stimulation Therapy for Mild Cognitive Impairment: Three Case Studies
JO  - OBM Geriatrics
SP  - 005
VL  - 02
IS  - 02
AB  - Background: Mild Cognitive Impairment [MCI] is a transition stage between normal aging and dementia. It seems to be useful to treat MCI before the onset of early dementia, though no pharmacological treatment is recommended [1]. These case studies aimed to assess the efficacy of long-term repetitive Transcranial Magnetic Stimulation [rTMS] treatment on cognition, and clinical changes, in elderly MCI patients. 
Methods: Three patients with MCI were treated by rTMS with different parameters of stimulation, targeting the Dorsolateral Prefrontal Cortex for three, six or twelve months. Cognition, depressive symptoms and overall clinical change were assessed before and after rTMS. 
Results: After treatment, all three MCI patients improved their cognition and overall clinical state. No depressive symptoms appeared. 
Conclusions: Our results highlight the cognitive and clinical benefits of long-term rTMS treatment in MCI patients, without side effects. These promising results must be confirmed in randomised double-blind studies in order to optimise rTMS parameters.
SN  - 2638-1311
UR  - https://doi.org/10.21926/obm.geriatr.1802005
DO  - 10.21926/obm.geriatr.1802005
ID  - Durand2018
ER  -