TY  - JOUR
AU  - Petrovic, Bojana
AU  - Komnenic Radovanovic, Milica
AU  - Erceg, Nikolina
AU  - Milicevic, Srboljub
AU  - Dusanovic Pjevic, Marija
PY  - 2024
DA  - 2024/01/17
TI  - Investigating Cytogenetic Profiles in Couples Experiencing Recurrent Implantation Failure Post<i> in vitro</i> Fertilization
JO  - OBM Genetics
SP  - 211
VL  - 08
IS  - 01
AB  - This study evaluates how chromosomal factors affect assisted reproduction techniques (ART) challenges among infertile couples, impacting their chances of conception. Chromosomal abnormalities, a leading cause of pregnancy failure and miscarriages, were investigated in a four-year retrospective study involving 100 patients with a history of infertility and unsuccessful IVF treatment. Among these cases, nine (9%) displayed aberrant chromosomal patterns, including balanced translocations (5%), sex chromosome deletions (3%), and one case of a small supernumerary marker chromosome (sSMC) (1%). The results of the present study highlight the importance of integrating comprehensive cytogenetic analysis as a routine diagnostic tool for individuals dealing with infertility, particularly before assisted reproduction techniques, to avert recurrent implantation failure and to enhance their chances of success.
SN  - 2577-5790
UR  - https://doi.org/10.21926/obm.genet.2401211
DO  - 10.21926/obm.genet.2401211
ID  - Petrovic2024
ER  -