TY  - JOUR
AU  - Roversi, Gaia
AU  - Redaelli, Serena
AU  - Villa, Nicoletta
AU  - Crosti, Francesca
AU  - Sala, Elena
AU  - Conconi, Donatella
PY  - 2019
DA  - 2019/01/28
TI  - Interphase FISH: A Helpful Assay in Prenatal Cytogenetics Diagnosis
JO  - OBM Genetics
SP  - 063
VL  - 03
IS  - 01
AB  - Since its introduction around the end of the 1970s, interphase in situ hybridization supports classical and latest techniques for determining foetal karyotype in the prenatal diagnosis, providing relevant information for the management of pregnancy quickly. Interphase FISH plays an important role in the study of pregnancies with malformations, in mosaicism conditions, in confirming or excluding aneuploidy detected by non-invasive prenatal testing and in diagnosis of contiguous gene syndromes due to microdeletions. 
The availability of many commercial probes from different genomic regions makes this method versatile and easy to apply in the path of diagnosis and foetal care.
SN  - 2577-5790
UR  - https://doi.org/10.21926/obm.genet.1901063
DO  - 10.21926/obm.genet.1901063
ID  - Roversi2019
ER  -