TY  - JOUR
AU  - Coviello, Domenico
AU  - Moog, Ute
PY  - 2018
DA  - 2018/09/13
TI  - Introduction to the Special Issue on Next Generation Sequencing: Short General Overview of NGS
JO  - OBM Genetics
SP  - 034
VL  - 02
IS  - 03
AB  - he publication of the double helix DNA structure in 1953 [1] was the kick-off of numerous efforts to understand and unravel the complexity of the human genome. It took 50 years until the human genome project, based on Sanger sequencing, was completed in 2003 [2]. This was followed by what may be considered a revolution in the field of DNA analysis: the introduction of Next Generation Sequencing (NGS) in 2005 consisting of massively parallel sequencing of DNA fragments which allows the high throughput analysis of large numbers of genes or of the whole genome [3].
SN  - 2577-5790
UR  - https://doi.org/10.21926/obm.genet.1803034
DO  - 10.21926/obm.genet.1803034
ID  - Coviello2018
ER  -