Open Access Original Research

A Comprehensive in Silico Analysis of the Functional and Structural Consequences of the Deleterious Missense Nonsynonymous SNPs in Human GABRA6 Gene

Received: 20 December 2023;  Published: 15 April 2024;  doi: 10.21926/obm.genet.2402227

Abstract

Epilepsy, a prevalent neurological disorder, affects more than 50 million individuals worldwide and is characterized by recurring seizures. Nonsynonymous single nucleotide polymorphisms (nsSNPs) found within coding regions of epilepsy-related genes are believed to have significant impacts on protein function. This is due to their tendency to cause mutat [...]

Open Access Original Research

Dietary Fiber in Preventing Non-Communicable Diseases: Predicting Prevented Deaths and Economic Impact through the Use of Algae as a Fiber Source

Received: 30 August 2023;  Published: 15 April 2024;  doi: 10.21926/rpn.2402006

Abstract

Non-communicable diseases (NCDs) are responsible for two-thirds of premature deaths in Europe. This added to the European socio-economic scenario already weakened by the vital aging of the population, contributes to the loss of active individuals, weakening competitiveness and social and economic sustainability, thus making the prevention of NCDs a [...]

Open Access Perspective

Whisker Bond: From Findings to Concept in Refractories

Received: 12 January 2024;  Published: 12 April 2024;  doi: 10.21926/rpm.2402010

Abstract

Ceramic bonds are conventionally formed during the burning of refractory bricks and by using pre-fabricated blocks or monolithic lining, which is characterized as the coalescence of the particles by liquid sintering. However, the whisker bond was discovered with the outstanding performance of unburnt periclase–spinel–Al bricks while substituting [...]

Open Access Original Research

Chest CT Scan Features of COVID-19 in a Hospitalized High-Altitude Population

Received: 30 November 2022;  Published: 12 April 2024;  doi: 10.21926/obm.genet.2402226

Abstract

There is a lack of knowledge regarding the type of lung compromise in high-altitude residents with COVID-19. This study aims to evaluate the lung compromise in chest CT scans of high-altitude dwellers hospitalized with COVID-19. Retrospective study that took place in "Daniel Alcides Carrión" Regional Hospital, located 3,250 meters above sea level in [...]

Open Access Original Research

Compassionate Love for a Romantic Partner among Brazilian College Students

Received: 08 February 2024;  Published: 12 April 2024;  doi: 10.21926/obm.neurobiol.2402217

Abstract

Compassionate love (CL) is a recent subject of close relationships. CL is focused on enlarging beneficence to another. The present study approaches the test of the psychometric characteristics of the shortened form of the Compassionate Love Scale for a partner (CLS-P-SF) for Brazilian college students and its relationships with background and well-being [...]

Open Access Review

Thrombotic Microangiopathy in Solid Organ Transplantation

Received: 31 January 2024;  Published: 10 April 2024;  doi: 10.21926/obm.transplant.2402211

Abstract

Thrombotic Microangiopathy (TMA) is a syndrome characterized by microangiopathic hemolytic anemia (MAHA) and thrombocytopenia. The presence of schistocytes on peripheral smear, a negative Coombs test, elevated lactate dehydrogenase, increased reticulocyte count and low haptoglobin are often the clues for MAHA. The microvascular process often targets [...]

Open Access Original Research

Attitudes and Motivations Towards Implantation of Intention Towards Exercise among Entrepreneurs: A Brain Freshness Activity

Received: 19 October 2023;  Published: 10 April 2024;  doi: 10.21926/obm.neurobiol.2402216

Abstract

In the contemporary landscape, developing individuals' attitudes, motivations, and intentions toward exercise and physical activities emerges as an imperative cornerstone for fostering a healthy and thriving lifestyle. The present study examines the effect of the theory of the planned behavior (TPB) constructs on exercise motivation (MT) and intention [...]

Open Access Review

Allelic Variation of High-Molecular-Weight Glutenin Genes in Triticum Species and Triticale (× Triticosecale Wittmack)

Received: 27 February 2024;  Published: 09 April 2024;  doi: 10.21926/obm.genet.2402225

Abstract

High-molecular-weight glutenin subunits (HMW-GS) encoded by alleles at the Glu-A1, Glu-B1, and Glu-D1 loci confer unique bread-making properties of common wheat (Triticum aestivum L.). The identification of HMW-GS is the prerequisite for pyramiding high-quality glutenin genes. The present review is designed to list all published HMW-GS alleles in Tritic [...]

Open Access Book Review

Book Review: Small Supernumerary Marker Chromosomes. Basics

Received: 21 February 2024;  Published: 09 April 2024;  doi: 10.21926/obm.genet.2402224

Abstract

This review provides a critical assessment of the content and structure of the recently published book by Dr. Thomas Liehr, 'Small Supernumerary Marker Chromosomes: Basics.'

Open Access Review

Osteoporosis Etiology, Epidemiology, Diagnosis, Diet, and Treatment: A Narrative Review

Received: 26 December 2022;  Published: 09 April 2024;  doi: 10.21926/obm.geriatr.2402277

Abstract

This narrative review aimed to select, gather, and present inclusive evidence about osteoporosis etiology, epidemiology, diagnosis, diet, and treatment. We searched PubMed and Google using these terms: osteoporosis AND etiology, osteoporosis AND epidemiology, osteoporosis AND diagnosis, osteoporosis AND diet, and osteoporosis AND treatment. Each title [...]

Open Access Editorial

Solid Catalysts – New Perspectives and Applications

Received: 31 March 2024;  Published: 09 April 2024;  doi: 10.21926/cr.2402004

Open Access Review

Andropause: A Neglected Disease Entity

Received: 11 January 2024;  Published: 03 April 2024;  doi: 10.21926/obm.geriatr.2402276

Abstract

This review aims to bring attention to the growing issue of andropause, a condition that affects men as they age. The literature was identified by searching the major bibliographic databases, including PubMed, Google Scholar, EBSCOhost, Web of Science, and CINAHL. Studies were included if they focused on strategies for reducing and preventing andropause [...]

Open Access Review

“Guess Who?” in the Creation of Hazardous and Non-Hazardous Diets through History

Received: 17 November 2023;  Published: 03 April 2024;  doi: 10.21926/rpn.2402005

Abstract

The relationship between obesity and weight loss treatments has run parallel throughout history; however, not all diets are suitable for improving one’s health. This review aims to categorize diets according to the new classification of hazardous diets established in 2021. A search was conducted across grey, white, and black literature. The results [...]

Open Access Review

Review on the Development of Titanium Diboride Ceramics

Received: 02 January 2024;  Published: 03 April 2024;  doi: 10.21926/rpm.2402009

Abstract

Titanium diboride (TiB2) materials have garnered significant attention due to their remarkable comprehensive properties. They offer potential applications in high-temperature structural materials, cutting tools, armor, electrodes for metal smelting, and wear-resistant parts. However, due to the low self-diffusion coefficient, the TiB2 exhibits poor [...]

Open Access Perspective

Leveraging Existing Abilities in Dementia (LEAD™): Changing the Way Rehabilitation Professionals Care for Persons Living with Dementia

Received: 08 December 2023;  Published: 03 April 2024;  doi: 10.21926/obm.geriatr.2402275

Abstract

Latest estimates indicate that 5-7% of the population are living with Alzheimer’s disease and related dementias worldwide with a doubling in incidence expected every 20 years. Rehabilitation professionals are challenged with the complex needs of these patients. It is commonly thought that patients with dementia do not benefit from rehabilitation becau [...]

Open Access Editorial

Acupuncture in Oncology – Update 2024

Received: 02 April 2024;  Published: 03 April 2024;  doi: 10.21926/obm.icm.2402022

Abstract

Acupuncture, as a promising complementary therapy for cancer patients, offers personalized symptom management and improved quality of life alongside conventional treatments. With its proven efficacy in alleviating chemotherapy-induced side effects such as nausea, fatigue, and pain, acupuncture stands as a holistic approach to cancer care. Tailored to [...]

Open Access Original Research

Design and Techno-Economic Evaluation of a Hybrid Mini-grid System for an Academic Institution

Received: 26 September 2023;  Published: 03 April 2024;  doi: 10.21926/jept.2402010

Abstract

Inadequate electricity supply is a global challenge that needs solutions. This situation has compelled the purchasing of fossil fuel-generating units for use in residential, commercial, and industrial sectors to generate electricity. However, using fossil fuel generating units cause greenhouse gas emissions, bringing about environmental pollution and [...]

Open Access Research Article

Local Authority Waste Management Strategies, the Circular Economy and the Generation of Energy from Waste in England

Received: 17 February 2024;  Published: 01 April 2024;  doi: 10.21926/jept.2402009

Abstract

The purpose of this article is to examine the approach to waste management of local authorities in England, to investigate their strategic objectives, and to ascertain to what extent sustainability and circular economy practices are in evidence in this context. A qualitative, inductive research method is used, based on an examination of secondary docume [...]

Open Access Review

Management of Steatosis in Living Donors: Where Do We Stand?

Received: 23 October 2023;  Published: 01 April 2024;  doi: 10.21926/obm.transplant.2402210

Abstract

With the progressive rise in rates of liver transplantation, stagnant donor pool, and social factors, living donor liver transplantation (LDLT) forms the majority of liver transplantations performed in Asian countries. As the global prevalence of metabolic-associated fatty liver disease (MAFLD) is increasing, around 17-25% of all the prospective donors [...]

Open Access Review

Airway Complications after Lung Transplantation

Received: 12 September 2023;  Published: 27 March 2024;  doi: 10.21926/obm.transplant.2401209

Abstract

Lung transplantation in patients with end stage lung disease can improve survival and quality of life. Airway complication incidence varies between 2-33%, but the true incidence is difficult to determine due to a lack of validated classification systems. There are many risk factors for post lung transplant airway complications, the most common being [...]

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