Adipose Tissue as a Useful Material for the Grafting of Tumorigenic Cells and Juvenile Tissues in MiceAbstract Although the aging process expands the adipose tissue habitation in mice and due to its close association with the female reproductive system, it can be easily exposed surgically under anesthesia when reproductive organs (including ovary, oviduct, and part of the [...] 418 5417 |
Economic Considerations in Using HCV and HIV Positive Donors for Kidney TransplantAbstract End Stage Renal Disease is becoming more prevalent in the United States of America, with demand for kidney transplant exceeding the available organ supply. A novel method to increase the donor pool has been to consider transplanting organs from deceased patients who have had Hepatitis C [...] 378 4392 |
Experience with Alpha-1 Proteinase Replacement Post-Lung Transplantation in Alpha-1 Antitrypsin Deficiency: A Single Center Case Seriesby
Kamyar Afshar
,
Michelle Bremer
,
Bharath Ravichandran
,
Ashley Feist
,
Eugene Golts
,
Elizabeth Schonhoft
and
Gordon Yung
Abstract Alpha-1 antitrypsin deficiency (AATD) accounts for approximately 5% of lung transplants (LTx) performed annually. No studies have addressed the potential benefit of ongoing alpha-1 proteinase inhibitor (A1-PI) replacement to AATD patients post-LTx. Our primary objective was to assess pot [...] 431 5598 |
Belatacept Dosing in Lung Transplantation: Is There a Method to the Madness?by
Christine Pham
,
Brett J Pierce
,
Simon W Yau
,
Jihad Georges Youssef
,
Ahmad Goodarzi
and
Howard J Huang
Abstract Data supporting the use of belatacept in non-abdominal organs are limited to case series and small cohorts involving patients requiring conversion due to CNI intolerance or contraindication. Review articles summarizing the efficacy of belatacept salvage therapy in lung transplantation ha [...] 678 6277 |
Defining Clinically Pathogenic HLA-Specific Antibodies - Granular Details in Characteristics in Pre and Early Time Following HLA-Antibody Incompatible Kidney TransplantationAbstract Antibodies against donor HLA determine access to solid organ transplantation and in many cases the outcome of transplantation, but graft failure is not an inevitable consequence of their presence. Much research has been performed with two main aims – which antibodies represent the highes [...] 547 4857 |
Predictors of Mid-Term Glomerular Filtration Rate after Deceased Donor Renal Transplantation: Kidney Donor Profile Index as a Predictor of Mid-Term GFRby
Oya Andacoglu
,
Jack Liu
,
Abigail Brooks
,
Amit Blumfield
,
Mehul Trivedi
,
Shoshana Lehman
,
Michael Parides
,
Enver Akalin
,
Jay Graham
,
Juan Rocca
and
Stuart Greenstein
Abstract Glomerular filtration rate (GFR) is an excellent indicator of renal function; however, it is rarely evaluated as an endpoint. We investigated donor and recipient factors for associations that might be predictive of mid-term GFR after renal transplantation. We performed a retrospective re [...] 467 4973 |
Sarcopenia; An Endemic in the Times of Pandemic in Liver TransplantationAbstract Liver transplantation (LT) has grown monumentally in the last 40 years. Sarcopenia has emerged as an independent factor associated with increased mortality in patients with end stage liver disease. In this review we aim to shed light upon recent developments in assessment, clinical impli [...] 602 4952 |
Efficacy of Autologous Stem Cell Transplantation for the Treatment of Multiple Myeloma in HIV-Positive PatientsAbstract Prior to the advent of anti-retroviral therapy (ART), autologous stem cell transplant (ASCT) was relatively contraindicated for multiple myeloma (MM) patients with human immunodeficiency virus (HIV) due to issues associated with stem cell harvest and the risk of opportunistic infections. [...] 564 4700 |
Macroscopic Aspergillus Infection at the Anastomosis of a Lung Transplant RecipientAbstract A 65-year-old female with a history of right lung transplantation (LTx) for chronic obstructive pulmonary disease (COPD) 9-years prior complicated by grade 3 bronchiolitis obliterans syndrome (BOS) was admitted to the hospital for chest pain and dyspnea on exertion (DOE). Her bronchoscop [...] 578 4371 |
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Open Access Short Communication Lack of Effect of Human Chorionic Gonadotropin in Mixed Lymphocyte Reaction in XenotransplantationAbstract It has been speculated that the immunomodulation associated with pregnancy, e.g., decreasing pro-inflammatory cytokines, increasing anti-inflammatory cytokines, upregulation of T regulatory cells (Tregs), is in part due to the effect of human chorionic gonadotropin (hCG). In this study, [...] 600 4168 |
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