Open Access Original Research

Non-Renal Factors Associated with Simultaneous Liver-Kidney Transplant in Patients with End-Stage Liver Disease and Stage 3-5 Chronic Kidney Disease Not Requiring Dialysis

by Alfonso Santos  , Amer Belal  , Hisham Ibrahim  and Muhannad Leghrouz

Received: 19 August 2022;  Published: 21 February 2023;  doi: 10.21926/obm.transplant.2301175

Abstract

We aimed to identify the non-renal risk factors for simultaneous liver-kidney transplantation (SLKT) vs. liver transplantation alone (LTA) in end-stage liver disease (ESLD) patients with estimated glomerular filtration rate (eGFR) <60 ml/min, not on dialysis. Using organ procurement and transplan [...]

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Open Access Review

Cytomegalovirus and Kidney Transplantation: An Update

by Michelle Senere  , Thaddeus Rogozinski  , J. Scott George  , Deepak Mital  and Douglas Slakey

Received: 08 November 2022;  Published: 29 January 2023;  doi: 10.21926/obm.transplant.2301174

Abstract

Cytomegalovirus (CMV) infection is the most common infection affecting kidney transplant recipients [1]. CMV may be present as asymptomatic viremia or with symptoms ranging from mild to significant tissue-invasive disease [1-3]. Optimal kidney graft function and survival requires that transplant car [...]

185 2071

Open Access Case Report

Lung Transplantation from A Donor with Previous SARS-CoV-2 Infection: 1-Year Outcomes

by Ashwini Arjuna  , Deepika Razia  , Devika Sindu  , Michael T. Olson  , Lara Schaheen  , Ross M. Bremner  , Rajat Walia  and Kendra McAnally

Received: 25 October 2022;  Published: 06 January 2023;  doi: 10.21926/obm.transplant.2301173

Abstract

Few reports have described successful lung transplantation from a donor with a history of SARS-CoV-2 infection, and outcomes beyond 3 to 6 months remain unknown. After weighing the urgency and life-saving benefits of lung transplantation against the risk of viral transmission, we successfully perfor [...]

119 1185

Open Access Editorial

Acknowledgement to Reviewers of OBM Transplantation in 2022

by OBM Transplantation Editorial Office

Received: 04 January 2023;  Published: 04 January 2023;  doi: 10.21926/obm.transplant.2301172

Abstract

The editors of OBM Transplantation would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2022. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal’s editorial process. We aim to recognize rev [...]

90 1001

Open Access Editorial

Islet Transplantation: How Much Have We Advanced and How to Keep Moving Forward?

by Braulio A. Marfil-Garza  and Tatsuya Kin

Received: 11 December 2022;  Published: 19 December 2022;  doi: 10.21926/obm.transplant.2204171

Abstract

EditorialIslet Transplantation: How Much Have We Advanced and How to Keep Moving Forward?Braulio A. Marfil-Garza ¹, Tatsuya Kin ^{1, 2 [...]}

Open Access Original Research

Shifting Pancreas Transplantation Rates and Demographics are the Culmination of Many Strategic Policy Changes

by Alma Rechnitzer  , Richard Teo  , Abigail Brooks  , Juan Rocca  , Nidal Mudhi  , Julia Torabi  , Maria Ajaimy  , Luz Liriano-Ward1  , Yorg Azzi  , Cindy Pynadath  , Pablo Loarte-Campos  , Enver Akalin  , Marie Le  , Milan Kinkhabwala  and Jay Graham

Received: 06 September 2022;  Published: 21 November 2022;  doi: 10.21926/obm.transplant.2204170

Abstract

The 2014 Pancreas Allocation System established national qualifying criteria for simultaneous kidney pancreas (SPK) transplantation. The 2019 UNOS Pancreas Transplantation Committee Policy 11.3.B modified these guidelines to expand transplantation. Subsequent effects on < [...]

188 1599

Open Access Opinion

"Let's Live Life - Let's Give Life”: Donor Program Improvement as the Key to Transplantation Success in 21^st Century - A Croatian Experience

by Katarina Tomulic Brusich

Received: 30 August 2022;  Published: 15 November 2022;  doi: 10.21926/obm.transplant.2204169

Abstract

Transplantation is a widely accepted and successful life-saving treatment for hundreds of thousands of patients. However, transplant medicine still faces a number of obstacles. One of the most significant is the large disparity between the number of donors and recipients and the growing [...]

124 1452

Open Access Original Research

Hepatitis B Reactivation in HBsAg Negative Renal Transplant Patients with Evidence of Previous HBV Infection: A Not Neglectable Occurrence

by Ana Paula Leopercio  , Christini Emori  , Elisabete Calore Neiva  , Ana Lucia Silva Souza  , Ana Cristina Amaral  , Gustavo Almeida Vieira  , Raimundo Araujo Gama  , Jose Osmar Medina-Pestana  and Maria Lúcia Ferraz

Received: 22 June 2022;  Published: 26 October 2022;  doi: 10.21926/obm.transplant.2204168

Abstract

Hepatitis B virus (HBV) infection is frequent among patients with chronic kidney disease (CKD). HBV reactivation after kidney transplant (KT) is more common in patients with HBsAg+; however, it can also occur in previously infected individuals, particularly those with HBsAg negative and [...]

181 1797

Open Access Interview

An Interview with Prof. Haval Shirwan

by OBM Transplantation Editorial Office

Received: 09 October 2022;  Published: 17 October 2022;  doi: 10.21926/obm.transplant.2204167

120 1821

Open Access Original Research

The P2X7 Receptor Antagonist AZ10606120 Does Not Alter Graft-Versus-Host Disease Development and Increases Serum Human Interferon-γ in a Humanized Mouse Model

by Nicholas J Geraghty  , Amal Elhage  , Peter Cuthbertson  , Debbie Watson  and Ronald Sluyter

Received: 06 June 2022;  Published: 06 September 2022;  doi: 10.21926/obm.transplant.2203166

Abstract

Allogeneic hematopoietic stem cell transplantation is a curative therapy for hematological malignancies, but its efficacy is limited by graft-versus-host disease (GVHD). This life-threatening disorder develops when donor (graft) immune cells cause inflammatory damage to recipient (host) tissues. The [...]

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