Thrombotic Microangiopathy in Solid Organ Transplantation
Abstract
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Thrombotic Microangiopathy in Solid Organ Transplantationby
Sravanthi Nandavaram
,
Hannah Twist
,
Rickey Evans
,
Sravanthi Paluri
,
Ana Castellanos
and
Andres Pelaez
Abstract Thrombotic Microangiopathy (TMA) is a syndrome characterized by microangiopathic hemolytic anemia (MAHA) and thrombocytopenia. The presence of schistocytes on peripheral smear, a negative Coombs test, elevated lactate dehydrogenase, increased reticulocyte count and low haptoglobin are often the clue [...] 78 486 |
Management of Steatosis in Living Donors: Where Do We Stand?Abstract With the progressive rise in rates of liver transplantation, stagnant donor pool, and social factors, living donor liver transplantation (LDLT) forms the majority of liver transplantations performed in Asian countries. As the global prevalence of metabolic-associated fatty liver disease (MAFLD) is i [...] 73 503 |
Airway Complications after Lung Transplantationby
Syed Nazeer Mahmood
and
Amit Mahajan
Abstract Lung transplantation in patients with end stage lung disease can improve survival and quality of life. Airway complication incidence varies between 2-33%, but the true incidence is difficult to determine due to a lack of validated classification systems. There are many risk factors for post lung tra [...] 62 510 |
Calculated Human Leucocyte Antigens Evolutionary Divergence (cHED)by
Bruno A Lima
Abstract Human Leucocyte Antigens (HLA) constitute a highly polymorphic set of genes pivotal to the immune response. The HLA heterozygous advantage hypothesis assumes that heterozygous individuals at the HLA level have a wider range of peptides for T cell recognition than homozygous individuals. Consequently [...] 71 531 |
Chronic Lung Allograft Dysfunction, a Review in 2023Abstract Chronic allograft dysfunction (CLAD) is one of the leading causes of death after lung transplantation [1]. CLAD is a progressive and irreversible decline in lung function after transplant, manifested as an obstructive, restrictive, or mixed ventilatory impairment without any identifiable [...] 101 832 |
Evaluation of Total Parenteral Nutrition in the Autologous Transplantation Setting in Patients with AML: A Retrospective Exploratory Analysisby
Sarah Willi
,
Ulrike Bacher
,
Marie Noelle Kronig
,
Michael Daskalakis
,
Lia Bally
and
Thomas Pabst
Abstract Malnutrition remains a clinical challenge in AML patients undergoing autologous hematopoietic stem cell transplantation (ASCT), leading to physical deconditioning and prolonged hospitalization. Prospective data are mainly lacking to identify those patients who may particularly benefit from parentera [...] 118 857 |
Acknowledgement to Reviewers of OBM Transplantation in 2023Abstract The editors of OBM Transplantation would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2023. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal’s editorial process. We aim to r [...] 135 972 |
Immune-Suppression Modulation in Solid Organ Transplant Recipients Admitted for COVID-19by
Francesco Peracchi
,
Giovanna Travi
,
Marco Merli
,
Roberto Rossotti
,
Fulvio Crippa
and
Massimo Puoti
Abstract SARS-CoV-2 infection has significantly impacted solid organ transplant (SOT) recipients, who are at high risk of disease and worse outcomes. Moreover, therapeutic management in this population is not precise yet. Our study aimed to evaluate the overall survival of SOT recipients and pred [...] 188 1471 |
Lung Donor Selection and Management: An Updated Reviewby
Shefali Mody
,
Soham Nadkarni
,
Shreyash Vats
,
Akshay Kumar
,
Sravanthi Nandavaram
and
Suresh Keshavamurthy
Abstract The shortage of donor lungs for transplantation is a major challenge, resulting in longer waitlist times for patients with a higher risk of waitlist mortality. It is crucial to continue promoting awareness about organ donation through legislation, public campaigns, and health care provider education [...] 281 2280 |
Acute Rejection of the Lung Allograft: Phenotypes and ManagementAbstract Treatment options for end stage lung diseases are limited to stabilizing lung failure, decreasing disease progression, and symptom management, but significant reversal of lost lung function is often not possible. For well selected patients, lung transplantation may be a viable option to improve both [...] 177 1679 |
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