Vidhi is a Clinical yoga therapist; mentor for yoga therapy training in Krishnamacharya tradition. She holds a MSc in Public health from Kings College London.

She is Complementary and Natural Health Council Profession Specific Board member for Yoga Therapy and Yoga Researcher in the NHS. She has authored articles in yoga and patient group magazines. She supported Central Middlesex Hospital (CMH) rheumatology patient group with patient driven audits and held first in UK pilot study of Yoga Therapy. She has published articles in complementary therapies in medicine and also abstracts in EULAR, Innovations in Medicine Conference for Royal College of Physicians and International Congress on Integrative Medicine and Health, Baltimore. She also completed her internship with London School of Hygiene and Topical medicine conducting a systematic review of behavioral interventions for chronic conditions in low and middle-income countries.

She is also on the mind-body medicine sub-committee supported by the Royal College of Medicine (RSM).

She teaches modular introductory course at Imperial College School of Medicine curriculum to their year medical students and was awarded Inspiration award 2017 (Runners Up). She delivers yoga therapy for the management of addiction in Rehab Clinics such as Promis Clinic as well as other trauma related physical and mental issues. She has collaborated with consultants and General Physicians around West London to deliver Yoga Therapy as a complementary healing modality.

Publications- Vidhi Sadana Sohdi

• Sadana Vidhi. (2020). Pariṇāma Model: Contextualizing Experiences of Change in Participants of Pilot Study to Determine Efficacy of Individualized Yoga Therapy in Rheumatoid Arthritis and Anxiety. Nat Ayurvedic Med 2020, 4(3): 00025. Doi: https://doi.org/10.23880/jonam-16000255.
• Cartwright Tina, Cahill Margaret, Sadana Vidhi (2020). A mixed methods evaluation of an individualised yoga therapy intervention for rheumatoid arthritis: Pilot study, Complementary Therapies in Medicine, Volume 50. Doi: https://doi.org/10.1016/j.ctim.2020.102339.
• Sadana Vidhi, Cartwright Tina, Cahill Margaret, Anie Kofi, Colaço Beranrd (2018). Yoga-therapy for rheumatoid arthritis: rapid improvement in PROMS, Ann Rheum Dis, volume 77, supplement Suppl, pp: A1852.
• Sadana Vidhi (2017). Confrence Report - Individualised Yoga Intervention, Yoga Therapy Today, International Association of of Yoga Therapy.
• Sohdi Vidhi, Colaço Beranrd, Hoffman M., Kirk J. (2017). Evaluation of Patient Compliance with Long Term Prescribed Rheumatic Medication at Local London Hospital Rheumatology Unit, Annals of the Rheumatic Diseases, volume 76, supplement 2, pp: 1545.
• Vidhi Sohdi (2016). Yoga for Whiplash, Holistic Therapist Magazine.
• Vidhi Sohdi (2016). Yoga for Anxiety, Spectrum Magazine, Summer edition.
• Vidhi Sohdi (2015). Yoga for Rheumatic Conditions, Spectrum Magazine, Autumn edition.
• Vidhi Sohdi (2015). How Yoga can Help Type 2 Diabetes, Diabetes Update, Diabetes UK Spring edition.
• Vidhi Sohdi (2015). Yoga for Diabetes, Spectrum Magazine, Winter edition.
• Vidhi Sohdi (2009). Yoga for Back Pain, On Form Magazine, The Times of Malta , July Issue.
• Vidhi Sohdi (2009). Yoga for Sleep Disordres, On Form Magazine, The Times of Malta, August Issue.
• Vidhi Sohdi (2009). Yoga for Menopause, On Form Magazine, The Times of Malta, September Issue.
• Vidhi Sohdi (2009). Yoga for Pregnancy, On Form Magazine, The Times of Malta, October Issue.
• Vidhi Sohdi (2009). Yoga for Breathing Disorders, On Form Magazine, The Times of Malta, November Issue.

Education

Electrical Engineering Faculty, Yerevan Politechnical Institute,

Yerevan, USSR, 1958-1963.

Post-graduate study for PhD (Candidate of technical Sciences),

Armenian Research Institute of Energetics (1966-1969).

Academic degrees and titles according to the USSR all-union qualification system

Academic degrees:

Candidate of Technical Sciences (PhD) in the speciality of “Electrical Engineering”.

Doctor of Biological Sciences in the specialities of “Human and animal physiology” and “Biophysics”.

Academic titles:

Senior Research Fellow in the speciality of “Biological and Medical Cybernetics”.

Professor in the speciality of “Control in Biological and Medical Systems (Including the Application of Computer Technology)”.

Employment History

2013 – till now; Director, Kaoskey PTY Limited, Sydney.

2013 – till now; Honorary Associate, Sydney Medical School, Sydney University.

2008 – 2012: Research Officer, Sydney Medical School-Western, Faculty of Medicine, Sydney University.

1996 – 2008: Hospital scientist, Department of Clinical Sciences, Westmead Hospital, NSW 2145, Australia.

1974 – 1995: Laboratory Head: Laboratory of Neural Systems Mathematical Modelling, Institute of Physiology under National Academy of Sciences of Armenia, Yerevan, Armenia (USSR).

1972-1974: Senior Scientific Officer, Laboratory Head: Laborartory of Functional Modelling of Biological Systems, The Institute of Experimental Biology under National Academy of Sciences of Armenia, Yerevan, USSR.

1964 – 1972: PhD student, Chief Engineer, Senior Scientific Officer:

Armenian Research Institute of Energetics, Yerevan, USSR.

1963: Assistant: The Chair of Electrical machines and apparatus,

Yerevan Politechnical Institute, Yerevan, USSR.

Fields of interest: Analysis and modeling of biological signals including EEG, ERP, ECG, VEP and EMG. Quantitative methods of psychophysiological research.

Grant awards:

Grant RYR000 from the International Science Foundation for the project: “The Coding Role of Facilitatory Synapses” (1994)

Linkage Grant HTECH.LG 930981 on the Priority Area on High Technology from the NATO scientific and environmental affairs division for the project “Simulation of Epileptogenesis via Computer Reconstructions of Neuronal Processes”, in collaboration with professor G. Kostopoulos (University of Patras, Greece). 1993-1995.

Publications: More than 90 scientific papers, and a monograph “Transients in Neuronal Systems”, Publ. House of Armenian Academy of Sciences, Yerevan, 1987.

Selected papers and patent application

• Patent application No. PCT/AU2014/050283 – D. Melkonyan. Decomposition of non-stationary signals into functional components (HMcIP ref: P31071PC00), 2014
• Melkonian D, Barin E. Non-linear dynamics and fractal composition of human electrocardiogram: a proposed universal formula for ECG waveforms. (2016) Fractal Geometry and Nonlinear analysis in Medicine and Biology 2(2), 1-9; DOI: 10.15761/FGNAMB.1000132
• Kozlowska, K, Melkonian, D, Spooner, C.J., Scher S., Meares, R. Cortical arousal in children and adolescents with functional neurological symptoms during the auditory oddball task. October 2016, Neuroimage Clinical 10/2016; DOI:10.1016/j.nicl.2016.10.016
• Melkonian D, Blumenthal T. (2013) Dynamics of the eyeblink EMG at global and microscopic scales. The Open Cybernetics and Systemics Journal 7, 11-22.
• Melkonian D, Korner A., Meares R., Bahramali H. (2012) Increasing sensitivity in the measurement of Heart Rate Variability: the method of Non-Stationary RR time-frequency analysis. Computer Methods and Programs in Biomedicine 108: 53-67.
• Melkonian D., Barin E., and Bahramali H. (2011) Chaotic dynamics of ECG waveforms at global and microscopic scales: theory and applications. The Open Cybernetics and Systemics Journal, 5, 16-28.
• Meares R., Schore A., Melkonian D. (2011) Is borderline personality a particularly right hemispheric disorder? A study of P3a using single trial analysis. Australian and New Zealand Journal of Psychiatry, 45: 131-139
• Melkonian D. (2010) Similar basis function algorithm for numerical estimation of Fourier integrals. Numerical algorithms, 54: 73-100.
• Bahramali, H., Melkonian, D., O’Connell, O. (2008) Self regulation of the heart: natural frequency and damping of the heart contractions. The Open Cybernetics and Systemics Journal 2, 1-10.
• Meares, R., Gerull,F., Korner, A., Melkonian, D., Stevenson, J., & Samir. H., (2008) Somatization and Stimulus Entrapment. Journal of The American Academy of Psychoanalysis and Dynamic Psychiatry, 36(1): 165-180.
• Melkonian, D., Meares, R., Bahramali, H., Harris, A., & Williams, L. (2007) Numerical Fourier transform spectroscopy of EEG waveforms using similar basis function algorithm. Trends in Applied Spectroscopy, 6: 69-77.
• Harris, A., Melkonian, D., Williams, L., & Gordon, E. (2006) Dynamic spectral analysis findings in first episode and chronic schizophrenia. International Journal of Neuroscience, 116: 223-246.
• Meares, R., Melkonian, D., Gordon, E., & Williams, L. (2005) Distinct pattern of P3a event-related potential in borderline personality disorder. NeuroReport, 16: 289-293.
• Hermens, D.F., Williams, L.M., Lazzaro, I.., Whitmont, S., Melkonian, D., & Gordon, E. (2004) Sex differences in adult ADHD: a double dissociation in brain activity and autonomic arousal. Biological Psychology, 66: 221–233.
• Melkonian, D., Blumenthal, T.D., & Meares, R. (2003) High resolution fragmentary decomposition – a model based method of non-stationary electrophysiological signal analysis. Journal of Neuroscience Methods, 131: 149-159.
• Blumenthal, T.D., & Melkonian, D. (2003) A model based approach to quantitative analysis of eyeblink EMG responses. Journal of Psychophysiology, 17:1-11.
• Melkonian, D., Gordon, E., & Bahramali, H. (2001) Single-event-related potential analysis by means of fragmentary decomposition. Biological Cybernetics, 85: 219-229.
• Melkonian, D., Blumenthal, T., & Gordon, E. (1999) Numerical Fourier transform spectroscopy of EMG half-waves: fragmentary-decomposition-based approach to nonstationary signal analysis. Biological Cybernetics, 81:457-467.
• Melkonian, D., Gordon, E., Rennie, C., & Bahramali, H. (1998) Dynamic spectral analysis of event-related potentials. Electroencephalography and Clinical Neurophysiology, 108: 251-259.
• Melkonian, D., & Kostopoulos, G.K. (1996) Stochastic particle formulation of the vesicle hypothesis. Relevance to short-term phenomena. NeuroReport, 7: 937-942.
• Melkonian, D., & Kostopoulos, G.K. (1996) Novel approach to a quantitative treatment of the quantal transmitter release at the frog neuromuscular junction. Neuroscience Letters, 209: 13-16.
• Melkonian D. (1993) Direct evidence for the synaptic resonance phenomenon. NeuroReport, 5: 217-220
• Melkonian D. (1993)Transient analysis of a chemical synaptic transmission. Biological Cybernetics, 68: 341-350
• Melkonian D. (1992) Pattern dependent form of synaptic modification and its quantal origins. NeuroReport, 3: 937-940
• Melkonian D. (1991) Double barrier quantal model of neurotransmitter relese. NeuroReport, 2: 719-722.
• Melkonian, D. (1990) Mathematical theory of chemical synaptic transmission. Biological Cybernetics, 62:539-548.

Mirela Olympia Fagarasan Palmer
P.O.Box 1054
Anaheim, CA 92815
Phone: (619) 204-3342
E-Mail: mirelafagarasan@netscape.net, olympiapalmer@yahoo.com

SUMMARY

I work in academia as an internationally recognized neuropharmacology and neuroimmunology researcher. I published more than 500 scientific reports in the field of neuropsychopharmacology and signal transduction . I am leading a laboratory interested in understanding the fundamental neurobiological mechanisms of neuropsychiatric disorders to contribute at development of new pharmacological treatments. We use genetic, neuroendocrine and neurochemical methods. We recognize the role of the immune system in modulating neuropsychiatric diseases and we are developing in vitro cellular models and in vivo animal models to study the neuro-immune interactions under normal and disease states I has successfully combined research, teaching, administration and clinical care and continue to work on advancing our understanding of serious mental illness and drug development. We used to translate research findings into medical practice for the purposes of diagnosing, preventing and treating diseases. I has published scientific reports on peptides, their receptors, signal transduction and the role of these neuropeptides in the immune systems. I hold patents for using modified peptides in the treatment of septic shock. I have skills and expertise in receptor pharmacology, immunohistochemistry, in vivo and in vitro cell culture, biochemistry, animal models, cell and molecular biology. I has lectured worldwide on these subjects and the others. I have 19 years of research experience with development and use of in vitro models to test compounds, such as receptor binding, receptor activation, signal transduction, receptor-receptor interactions, and induction of changes in cell cycle, proliferation and apoptosis. Furthermore I validated appropriate assays and models of diseases, screen compounds, and study mechanisms of action.

EDUCATION

Ph.D. in Neuroendocrinology

WORK EXPERIENCE

SELECTED PUBLICATIONS

• Fagarasan, M. O.; Galea, V.; Toader, S.: "Chronic poisoning with trifluoperazine in rats. Kinetics of metabolites and hematologic changes." Clujul Medical, 57(2): 143-146, 1984.
• Fagarasan, M. O Quai, I.; Popa, L.;.: "Histopathological neuronal changes in acute intoxications with psychotropic drugs." Probleme de Medicine Legala, 17-18: 206-209, 1985.
• Fagarasan, M. O.; Fagarasan, E.: "Determination of hydroxi-metabolites of amitriptyline by mass spectrometry. Revista de Chimie, 37 (8): 775-726, 1986.
• Fagarasan, M. O.; Eskay, R.; Axelrod, J.: "Interleukin 1 potentiates the secretion of beta-endorphin induced by secretagogues in a mouse pituitary cell line (AtT-20). Proc. Natl. Acad. Sci. USA, 86: 2070-2073, 1989.
• Fagarasan, M. O.; Axelrod, J.: "Interleukin 1 amplifies the action of pituitary secretagogues via protein kinases. International J. Neurosci., 51, 311-313, 1990.
• Fagarasan, M. O.; Bishop, J. F.; Rinaudo, M. S.; Axelrod, J.: "Interleukin 1 induces early protein phosphorylation and requires only a short exposure for late induced secretion of beta-endorphin in a mouse pituitary cell line." Proc. Natl. Acad. Sci. USA, 87, 2229-2555, 1990.
• Fagarasan, M. O.; Aiello, F.; Muegge, K.; Durum, S.; Axelrod, J.: "Interleukin 1 induces beta-endorphin secretion via Fos and Jun in AtT-20 pituitary cells. Proc. Natl. Acad. Sci. USA, 87, 7871-7874, 1990.
• Fagarasan, M. O.; Axelrod, J.; Catt, J. K.: "Interleukin 1 potentiates agonist induced secretion of beta-endorphin in anterior pituitary cells." Biochem. and Biophys. Res. Comm. 173 (3): 988-993, 1990.
• Fagarasan, M. O.; Arora, P. V.; Axelrod, J.: "Interleukin 1 potentiates the secretion of b-endorphin induced by secretagogues: Dynamics of interleukin 1 internalization in pituitary cells. Prog. Neuro-Psychopharmacol. Biol. Psychiat., 15, 551-560, 1991.
• Fagarasan, M. O.: "Effects of IL-1 on AtT-20 cells: Methods and Overview. Neurobiology of Cytokines. Methods in Neurosciences, Vol. 16, Erol de Souza, (ed.) 327-341, 1993.
• Moody, T. W.; Fagarasan, M. O.; Zia, F.; Cesnjoy, M.; Goldstein, A. L.: "Thymosin Alpha 1 down regulates the growth of human non-small cell lung cancer cells in vitro and in vivo". Cancer Res., 53, 5214-5218, 1993.
• Moody, T.; W.; Zia, F. Venugopal; R., Korman, L. ,Y.; Goldstein A., L, Fagarasan, M. O.,: " Corticotropin -Releasing Factor stimulate cyclic AMP, arachidonic acid release and growth of lung cancer cells." Peptides, 15, (2): 281-285, 1994.
• Zia, F.; Fagarasan, M. O.: Bitar, K.; Coy, D.,H., Pisegna, J.,R.; Wang, S., A., Moody, T.,W. " Pituitary adenilate cyclase activating peptide receptors regulate the growth of non-small lung cancer cells" Cancer Research 55(21): 4886-91, 1995.
• Moody, T.,W.; Fagarasan, M. O.; Zia, F., " Neuromedin B stimulates arachidonic acid release, c-fos gene expression and the growth of c6 glioma cells". Peptides, 16, (6), :1133-1140., 1995.
• Knight, M., Fagarasan, M. O.; Takahashi, K., Gebblaoui, A., Z., Ma,Y., Ito, Y. Separation and purification of peptides by high -speed counter-current chromatography." J. Chromatogr. A, 702 (1-2) :207-214, 1995.
• Moody, T., W; Zia, F.; Venugopal, R.; Fagarasan, M. O.; Oie, H.; Hu, V. " GRP receptors are present in non small cell lung cancer cells" J. of Cellular Biochemistry., Supplement , 24 : 247-56, 1996.
• Fagarasan, M. O,; Aisen, P. S.: "IL-1 and Anti-inflammatory drugs modulate Amyloid beta cytotoxicity in PC12 cells" . Brain Research 723, 231-234, 1996.
• Fagarasan, M. O.; Efthimioupolos, S.: " Mechanism of amyloid beta-peptide (1-42) toxicity in PC12 cells." Molecular Psychiatry 1, 398-403, 1996.
• Fagarasan, M. O.; Sevilla D.; Baruch B.; Santoto J.; Marin D.; and Aisen P.S.: Plasma C3a levels in Alzheimer’s disease. Alzheimer’s Research 3, 137-140, 1997.
• Badamchian, M; Fagarasan, M.O.; Danner, R.L., Goldstein, A.L. : Thymosin beta 4 reduces lethality and down regulates inflammatory mediators in endotoxin-induced septic shock. “Int. J. of Imm. Pharm”. 2003

PATENTS

• Method of treating septic shock using thymosin beta 4.
• Method of treating septic shock by preventing actin polymerization.