Welcome to the new academic journal OBM Hepatology and Gastroenterology. Recent progress in understanding liver, biliary, pancreatic and gastro-intestinal diseases and their treatments has been observed in the world. OBM Hepatology and Gastroenterology publishes interesting and informative reviews, original articles, and invaluable case reports in this area. We also publish basic research as well as clinical research.

Hepatitis A virus (HAV), HBV, HCV, HDV, and HEV are still a serious issue worldwide. Treatments on these viruses have recently improved. However, liver fibrosis, cirrhosis and hepatocellular carcinoma are still critical conditions. We focus on all of these liver diseases. We also focus on broad-spectrum of gastro-intestinal diseases in this journal.

Please accept our special thanks for choosing to publish in the OBM Hepatology and Gastroenterology. We are looking forward to your submissions for OBM Hepatology and Gastroenterology.

Archiving: full-text archived in CLOCKSS.

Rapid publication: manuscripts are undertaken in 6.8 days from acceptance to publication (median values for papers published in this journal in 2020, 1-2 days of FREE language polishing time is also included in this period).

Free Publication in 2021
Current Issue: 2021  Archive: 2020 2019 2018 2017

Special Issue

Gastroesophageal Reflux Disease: From Heartburn to Esophageal Adenocarcinoma

Submission Deadline: June 30, 2021 (Open) Submit Now

Guest Editor

Massimo Arcerito, MD, FACS

General Surgeon and Surgical Oncologist, Department of General and Vascular Surgery, Riverside Medical Clinic Inc., Riverside, CA, USA

Website | E-Mail

Research Interests: Gastrointestinal Diseases including cancer; gastroesophageal functional diseases, esophageal and gastric cancer, laparoscopic and robotic surgery, hepato-biliary-pancreatic surgery

About this Topic

Gastroesophageal Reflux Disease (GERD) represents the most common upper gastrointestinal manifestation in the world.  This disease, which is managed medically and following simple life style changes by the majority of patients, might harbor more serious and long-lasting form of acid reflux, like peptic stricture and Barrett’s esophagus. Heartburn is the commonest symptoms, but additional symptoms like regurgitation, chest pain, dysphagia, odynophagia and cough transform the treatment of GERD in a multidisciplinary approach. The weakness of the lower esophageal sphincter and hiatal hernia are the two main reasons why GERD is recognized. Barrett’s metaplasia represents a precancerous lesion which might lead to esophageal adenocarcinoma. I envision a series of events from heartburn to esophageal adenocarcinoma, passing through GERD and Barrett’s esophageal metaplasia, with a unique opportunity to stop this lethal cascade. All our Barrett’s patients should be enrolled in a strict surveillance endoscopic program. The role of diagnostic tests, medical treatment and fundoplication with its long term clinical outcome should be emphasized.  The main purpose of this special issue is to create an algorithm to minimize the chance for our patients to develop esophageal adenocarcinoma on Barrett’s, which I see it as a medical failure in our daily clinical practice.


Manuscripts should be submitted online at http://www.lidsen.com/account-login by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. Guidelines for authors and other relevant information for submission of manuscripts are available on the Instructions for Authors page. OBM Hepatology and Gastroenterology is an international peer-reviewed Open Access monthly journal published by LIDSEN. Please visit the Instructions for Authors page before submitting a manuscript.
We sincerely invite investigators to contribute original research and review articles for this special issue, and we hope it will advance the research of Gastroesophageal Reflux Disease.


Open Access Review

Gastro-Esophageal Reflux in the Newborn: Pathologic Event or Does Spit Happen?

Received: 19 April 2021;  Published: 13 August 2021;  doi: 10.21926/obm.hg.2103060


Infants admitted to Neonatal Intensive Care Units (NICUs) are among the most vulnerable patients in medicine and are at risk for a variety of morbidities, many of which require pharmacologic therapy. Gastroesophageal Reflux Disease (GERD) is a common diagnosis in the NICU patient populat [...]
Open Access Original Research

The Timing of Endoscopic Evaluation of Anti-TNFα Therapy Patients with Ulcerative Colitis

Received: 10 August 2020;  Published: 09 July 2021;  doi: 10.21926/obm.hg.2103058


Anti-TNFα Therapy are used to induce remission and as maintenance therapy in refractory ulcerative colitis (UC) to achieve mucosal healing (MH). However, the time at which mucosal healing [...]
Open Access Review

The Physiology of Esophageal Reflexes

Received: 17 August 2020;  Published: 02 November 2020;  doi: 10.21926/obm.hg.2004052


Several digestive tract reflexes involving the esophagus and its sphincter muscles have been identified, but to date, no comprehensive review has addressed most of these reflexes. The current review presents the known physiology of different esophageal reflexes in which either the esophagus or its s [...]